Acne - Akneehttps://en.wikipedia.org/wiki/Acne
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References Diagnosis and treatment of acne 23062156Aknee, die mees algemene veltoestand in die Verenigde State, is 'n aanhoudende inflammatoriese velprobleem. Behandeling is daarop gemik om vier hooffaktore wat bydra tot aknee aan te spreek: oormatige talgproduksie, velselopbou, Propionibacterium acnes kolonisasie en gevolglike inflammasie. Aktuele retinoïede bestuur beide inflammatoriese en nie-inflammatoriese letsels effektief deur komedone te voorkom en te verminder terwyl inflammasie aangespreek word. Benzoylperoksied, beskikbaar oor-die-toonbank, is 'n bakteriedodende middel sonder om bakteriese weerstand te bevorder. Terwyl aktuele en orale antibiotika alleen werk, verbeter die kombinasie daarvan met aktuele retinoïede hul doeltreffendheid. Die byvoeging van benzoylperoksied by antibiotikaterapie verlaag die risiko van bakteriële weerstand. Orale isotretinoïen, goedgekeur vir ernstige en hardnekkige aknee, word deur die iPLEDGE-program toegedien.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Guidelines of care for the management of acne vulgaris 26897386Algemene aktuele behandelings vir aknee sluit benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents in. Orale antibiotika is lank reeds 'n belangrike deel van aknee-behandeling, veral vir matige tot ernstige gevalle. Hulle werk die beste wanneer dit saam met 'n aktuele retinoïed en BP gebruik word. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin het almal bewyse van doeltreffendheid getoon.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Acne Vulgaris: Diagnosis and Treatment 31613567Aktuele retinoïede word altyd aanbeveel vir die behandeling van aknee. Wanneer sistemiese of aktuele antibiotika gebruik word, is dit belangrik om dit met benzoylperoksied en retinoïede te kombineer, maar net vir tot 12 weke. Isotretinoin is gereserveer vir ernstige gevalle van aknee wat nie op ander behandelings gereageer het nie. Alhoewel daar bewyse is vir fisiese behandelings soos laserterapie en chemiese afskilfering, sowel as aanvullende benaderings soos gesuiwerde byegif en sekere diëte, is die doeltreffendheid daarvan nog onseker.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Effects of Diet on Acne and Its Response to Treatment 32748305 NIH
Verskeie studies het gekyk na hoe verskillende kosse aknee by pasiënte beïnvloed. Hulle het gevind dat mense met aknee wat kos eet met 'n lae glukemiese lading geneig is om minder aknee kolle te hê in vergelyking met diegene wat kos eet met 'n hoë glukemiese lading. Suiwel is ook bestudeer in verband met aknee. Dit blyk dat sekere proteïene in melk meer tot aknee kan bydra as die vet of algehele suiwelinhoud. Ander navorsing het gefokus op omega-3-vetsure en γ-linoleïensuur. Dit dui daarop dat mense met aknee kan baat by die eet van meer vis en gesonde olies om hul inname van hierdie vetsure te verhoog. Onlangse studies oor probiotika vir aknee toon belowende resultate, maar meer navorsing is nodig om hierdie vroeë bevindings te bevestig.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
By beide geslagte blyk hormone genaamd androgene deel te wees van die onderliggende meganisme, deur verhoogde produksie van talg te veroorsaak. Nog 'n algemene faktor is die oormatige groei van die bakterie Cutibacterium acnes, wat op die vel voorkom.
Behandelings wat direk op die aangetaste vel toegepas word, soos azelaïensuur, benzoylperoksied en salisielsuur, word algemeen gebruik. Antibiotika en retinoïede is beskikbaar in formulerings wat op die vel toegedien word en per mond geneem word vir die behandeling van aknee. Weerstand teen antibiotika kan egter ontwikkel as gevolg van antibiotika terapie. Verskeie soorte geboortebeperkingspille kan help om aknee by vroue te voorkom. Vroeë en aggressiewe behandeling van aknee met behulp van isotretinoïen kan nuttig wees om die langtermyn-komplikasies op individue te verminder.
○ Behandeling
Adapalene-jel kan wyd gebruik word omdat dit die afskeiding van sebum onderdruk en die effek het om die herhaling van aknee te onderdruk. Adapalene-gel kan die vel irriteer as te veel aanvanklik toegedien word. Benzoylperoksied en azelaïensuur, aan die ander kant, kan op inflammatoriese aknee-webwerwe gebruik word omdat dit help met inflammasie. Oor die algemeen is langtermynbehandeling van 1 maand of meer nodig om 'n effek te sien.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction