Cafe au lait maculehttps://en.wikipedia.org/wiki/Café_au_lait_spot
Cafe au lait macule is plat, hipergepigmenteerde geboortemerke.

Café au lait kolle verskyn in gesonde mense, maar kan geassosieer word met sindrome soos neurofibromatose tipe 1. Die aantal kolle kan kliniese betekenis hê vir die diagnose van neurofibromatose. Ses of meer kolle van ten minste 5 mm in deursnee in pre-pubertale kinders en ten minste 15 mm in post-pubertale individue is een van die belangrikste diagnostiese kriteria van neurofibromatose.

Café au lait kolle is gewoonlik teenwoordig by geboorte, permanent, en kan mettertyd in grootte groei of in getal toeneem. Selfs na laserchirurgie word die kolle dikwels nie heeltemal verwyder nie of kan dit na behandeling herhaal.

Behandeling
Die herhalingsyfer is gewoonlik hoog en laserbehandeling word vir 'n baie lang tyd vereis.
#QS1064 / QS532 laser
☆ In die 2022 Stiftung Warentest-resultate van Duitsland was verbruikerstevredenheid met ModelDerm net effens laer as met betaalde telemedisyne-konsultasies.
  • Eenvormig gekleurde grense en duidelike kolle verskyn dikwels in die kinderjare. Oor die algemeen is die grense duideliker as dié in hierdie prent.
  • Cafe au lait macule gesien in Neurofibromatosis type 1 (NF-1)
References Laser treatment for Cafe-au-lait Macules: a systematic review and meta-analysis 37291616 
NIH
Laserbehandeling het 'n 50% opruimingskoers getoon vir 75% van CALM pasiënte, met 43% wat 'n 75% opruimingskoers behaal het. Onder verskillende lasertipes het QS-1064-nm Nd:YAG die doeltreffendste resultate gehad. In die algemeen het alle lasertipes lae newe-effekte gehad, soos hipopigmentasie en hiperpigmentasie, wat goeie veiligheid aandui.
To draw a conclusion, the laser treatment could reach an overall clearance rate of 50% for 75% of the patients with CALMs, for 43.3% of the patients, the clearance rate could reach 75%. When looking at different wavelength subgroups, QS-1064-nm Nd:YAG laser exhibited the best treatment capability. Laser of all the wavelength subgroups presented acceptable safety regarding of the low occurrence of side effects, namely, hypopigmentation and hyperpigmentation.
 Cutaneous manifestations in neurofibromatosis type 1 32901776
Café-au-lait macules were shown in 1063 patients (96.5%), axillary and inguinal freckling in 991 (90%) and neurofibromas in 861 (78.1%). Other skin manifestations included: lipoma (6.2%), nevus anemicus (3.9%), psoriasis (3.4%), spilus nevus (3.2%), juvenile xanthogranuloma (3.2%), vitiligo (2.3%), Becker's nevus (1.9%), melanoma (0.7%) and poliosis (0.5%).
 Pigmentation Disorders: Diagnosis and Management 29431372
Pigmentation disorders are commonly diagnosed, evaluated, and treated in primary care practices. Typical hyperpigmentation disorders include postinflammatory hyperpigmentation, melasma, solar lentigines, ephelides (freckles), and café au lait macules.