Drug eruption - Dwelm Uitbarsting
☆ In die 2022 Stiftung Warentest-resultate van Duitsland was verbruikerstevredenheid met ModelDerm net effens laer as met betaalde telemedisyne-konsultasies.
Dwelm Uitbarsting (Drug eruption) word gekenmerk deur die invloed van die hele liggaam.
References
Velreaksies wat veroorsaak word deur medikasie, bekend as dwelmuitbarstings, kan soms ernstig wees. Hierdie ernstige reaksies, genaamd severe cutaneous adverse drug reactions (SCARs) , word as lewensgevaarlik beskou. Dit sluit voorwaardes soos Stevens-Johnson syndrome (SJS) , toxic epidermal necrolysis (TEN) , acute generalized exanthematous pustulosis (AGEP) , and drug reaction with eosinophilia and systemic symptoms (DRESS) in. Terwyl SCARs skaars is, ervaar ongeveer 2% van gehospitaliseerde pasiënte dit.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
’n 31-jarige vrou het die dermatologie-afdeling besoek met ’n pynlose rooi kol bo-op haar regtervoet. Sy het die vorige dag een dosis doksisiklien (100 mg) geneem, na 'n pikosekonde-laserbehandeling vir aknee-littekens. Verlede jaar het sy 'n soortgelyke probleem op dieselfde plek ervaar nadat sy dieselfde dosis doksisiklien na-laserbehandeling geneem het. Sy het geen noemenswaardige mediese geskiedenis nie en geen ander simptome, soos koors, plaaslik of regdeur haar liggaam nie.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson syndrome (SJS) en toxic epidermal necrolysis (TEN) is twee vorme van 'n ernstige velreaksie, verskillend van ander veltoestande soos erythema multiforme major en stafilokokke-gebrand vel-sindroom, sowel as geneesmiddelreaksies. SJS/TEN is 'n seldsame en ernstige reaksie wat wydverspreide vel- en slymvliesskade veroorsaak, dikwels met sistemiese simptome. In meer as 80% van die gevalle is medikasie die oorsaak.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Dwelm-uitbarstings word hoofsaaklik uit die mediese geskiedenis en kliniese ondersoek gediagnoseer. ’n Velbiopsie, bloedtoetse of immunologiese toetse kan ook nuttig wees.
Voorbeelde van algemene middels wat die uitbarsting veroorsaak, is antibiotika en ander antimikrobiese middels, sulfa-middels, niesteroïdale anti-inflammatoriese middels (NSAIDs), chemoterapie-middels vir maligniteite, antikonvulsante en psigotropiese middels.
○ Diagnose en behandeling
As jy koors het (verhoogde liggaamstemperatuur), moet jy so gou moontlik mediese hulp soek. Die vermeende geneesmiddel moet gestaak word (bv. antibiotika, nie-steroïdale anti-inflammatoriese middels). Voordat u die hospitaal besoek, kan orale antihistamiene soos setirisien of loratadien help vir jeuk en uitslag.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Bloedtoets (CBC, LFT, eosinofieletelling)
Mondelinge steroïede en antihistamiene met dokter se voorskrif