Herpes simplexhttps://af.wikipedia.org/wiki/Herpes_simplex
Herpes simplex is 'n virusinfeksie (herpesvirus). Infeksies word gekategoriseer op grond van die deel van die liggaam wat besmet is. Mondherpes is 'n algemene siekte en behels die gesig of mond. Dit kan lei tot klein blase in groepe wat dikwels koue sere of koorsblare genoem word. Genitale herpes, dikwels bloot bekend as herpes, kan ligte simptome hê of blase vorm wat oopbreek en klein maagsere tot gevolg het. Hierdie genees tipies oor twee tot vier weke. Tintelingpyne kan voorkom voordat die blase verskyn. Die eerste episode is dikwels ernstiger en kan geassosieer word met koors, spierpyne, geswelde limfknope en hoofpyne. Ander afwykings wat deur herpesvirus veroorsaak word, sluit in: herpetic whitlow wanneer dit die vingers behels, herpes van die oog, en neonatale herpes wanneer dit 'n pasgeborene affekteer.

Daar is twee tipes herpes simplex -virus, tipe 1 (HSV-1) en tipe 2 (HSV-2). HSV-1 veroorsaak meer algemeen infeksies rondom die mond terwyl HSV-2 meer algemeen genitale infeksies veroorsaak. Hulle word oorgedra deur direkte kontak met die besmette individu. Genitale herpes word geklassifiseer as 'n seksueel oordraagbare infeksie. Dit kan tydens bevalling na 'n baba versprei word. Na infeksie word die virusse langs sensoriese senuwees na die senuwee-selliggame vervoer, waar hulle lewenslank woon. Oorsake van herhaling kan insluit: verminderde immuunfunksie, stres en blootstelling aan sonlig.

In die meeste gevalle word antivirale middels slegs geneem wanneer simptome ernstig is. Daaglikse antivirale medikasie kan voorgeskryf word aan iemand wat baie gereelde infeksie het. Daar is geen beskikbare entstof nie en die gordelroos-entstof voorkom nie herpes simplex nie. Behandelings met antivirale medikasie soos aciklovir of valaciklovir kan die erns van simptome verminder.

Wêreldwye koerse van óf HSV-1 óf HSV-2 is tussen 60% en 95% by volwassenes. HSV-1 word gewoonlik tydens die kinderjare besmet. 'n Geskatte 536 miljoen mense wêreldwyd (16% van die bevolking) is vanaf 2003 met HSV-2 besmet, met groter syfers onder vroue en diegene in die ontwikkelende wêreld. Die meeste mense met HSV-2 besef nie dat hulle besmet is nie.

Behandeling ― OTC-dwelms
Vermy enige fisiese kontak, soos om 'n kind te soen, terwyl die blase teenwoordig is, aangesien kontak die infeksie na ander mense kan versprei. Jy moet rus sonder om alkohol te drink.
#Acyclovir cream
☆ In die 2022 Stiftung Warentest-resultate van Duitsland was verbruikerstevredenheid met ModelDerm net effens laer as met betaalde telemedisyne-konsultasies.
  • Herpes simplex op die lip.
  • Herpes simplex ― Herpes simplex-infeksie in vingers is meer algemeen by jong kinders as by volwassenes.
  • As simptome ernstig is, is die neem van antivirale medikasie die meeste nuttig om simptome te verlig.
  • As dit om die mond voorkom, moet angular cheilitis onderskei word. In hierdie prentjie is dit egter meer geneig om herpes te wees, aangesien daar verskeie klein blase om die mond is.
  • Herpes gingiva ― Herpesinfeksies kan nie net rondom die mond voorkom nie, maar ook in intraorale, perinasale en periokulêre areas.
  • Herpes genitalis by wyfies.
  • Herpes op die boude word gekenmerk deur terugvalle wanneer moeg is.
  • In gevalle van wydverspreide infeksie kan intensiewe behandeling vereis word, soos met herpes zoster.
References Herpes Simplex Type 1 29489260 
NIH
HSV-1-infeksie vorder deur primêre infeksie van epiteelselle, gevolg deur latensie, hoofsaaklik in neurone, en heraktivering. HSV-1 veroorsaak gewoonlik aanvanklike en herhalende vesikulêre uitbarstings, hoofsaaklik op die mond en genitale mukosa. Die manifestasies daarvan wissel van orolabiale herpes tot verskeie toestande soos herpetiese follikulitis, velinfeksies, okulêre betrokkenheid en ernstige gevalle soos herpes-enkefalitis. Antivirale terapie help om HSV-infeksie te bestuur.
Herpes simplex virus type 1 (HSV-1) is a member of the Alphaherpesviridae subfamily. Its structure is composed of linear dsDNA, an icosahedral capsid that is 100 to 110 nm in diameter, with a spikey envelope. In general, the pathogenesis of HSV-1 infection follows a cycle of primary infection of epithelial cells, latency primarily in neurons, and reactivation. HSV-1 is responsible for establishing primary and recurrent vesicular eruptions, primarily in the orolabial and genital mucosa. HSV-1 infection has a wide variety of presentations, including orolabial herpes, herpetic sycosis (HSV folliculitis), herpes gladiatorum, herpetic whitlow, ocular HSV infection, herpes encephalitis, Kaposi varicelliform eruption (eczema herpeticum), and severe or chronic HSV infection. Antiviral therapy limits the course of HSV infection.
 Herpes Simplex Type 2 32119314 
NIH
Herpes simplex virus type 2 (HSV-2) is 'n wydverspreide infeksie wat ongeveer 22% van volwassenes van 12 en ouer raak, altesaam 45 miljoen volwassenes in die Verenigde State. Terwyl HSV-1 tipies mondsere veroorsaak, kan dit ook tot genitale letsels lei. Wanneer pasiënte egter genitale letsels het, is HSV-2 gewoonlik die grootste bekommernis. Die simptome van HSV-2-uitbrake is dikwels vaag, soos genitale jeuk en irritasie, wat diagnose en behandeling kan vertraag. Hierdie vertraging kan lei tot verdere oordrag na onbesmette individue.
Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present with genital lesions. Despite this, most outbreaks of the infection will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.
 Prevention and Treatment of Neonatal Herpes Simplex Virus Infection 32044154 
NIH
Herpes simplex virus (HSV) veroorsaak gewoonlik infeksies soos genitale herpes en koue sere by tieners en volwassenes. Wanneer HSV 'n baba binne die eerste 4-6 weke van die lewe besmet, kan dit lei tot ernstige siekte met ernstige gevolge. Die vinnige diagnose van neonatale HSV-infeksie is noodsaaklik om te keer dat die siekte vererger, en om neurologiese probleme (selfs die dood) te voorkom.
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death.
 Herpes simplex virus infection in pregnancy 22566740 
NIH
Herpes simplex infeksie is baie algemeen en kan van swanger vroue na hul babas oorgedra word. Hierdie virus kan ernstige gesondheidsprobleme of selfs dood by pasgeborenes veroorsaak. Alhoewel dit skaars is tydens swangerskap self, gebeur dit dikwels tydens bevalling. Die risiko is die hoogste as die moeder in die latere stadiums van swangerskap besmet raak. Hierdie risiko kan egter verminder word deur antivirale middels te gebruik of te kies vir 'n C-afdeling in sekere situasies.
Infection with herpes simplex is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn. Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in the uterus, it occurs frequently during the transmission delivery. The greatest risk of transmission to the fetus and the newborn occurs in case of an initial maternal infection contracted in the second half of pregnancy. The risk of transmission of maternal-fetal-neonatal herpes simplex can be decreased by performing a treatment with antiviral drugs or resorting to a caesarean section in some specific cases.
 Clinical management of herpes simplex virus infections: past, present, and future 30443341 
NIH
Herpes simplex virus (HSV) tipes 1 en 2 besmet baie mense wêreldwyd. Gewoonlik bly die virus stil in senuweeselle nadat dit die vel besmet is, maar dit kan later heraktiveer, wat koue sere veroorsaak. Soms lei dit tot ernstige probleme soos ooginfeksies, breinontsteking of gevaarlike toestande by pasgeborenes en mense met swak immuunstelsels. Terwyl huidige medisyne help om infeksies te beheer, bly die risiko van dwelmweerstand en newe-effekte 'n bekommernis. Ons het nuwe middels nodig om die virus beter te teiken.
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human population. Most commonly, virus replication is limited to the epithelia and establishes latency in enervating sensory neurons, reactivating periodically to produce localized recurrent lesions. However, these viruses can also cause severe disease such as recurrent keratitis leading potentially to blindness, as well as encephalitis, and systemic disease in neonates and immunocompromised patients. Although antiviral therapy has allowed continual and substantial improvement in the management of both primary and recurrent infections, resistance to currently available drugs and long-term toxicity pose a current and future threat that should be addressed through the development of new antiviral compounds directed against new targets.