Hidradenitis suppurativa
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Hidradenitis suppurativa (stadium I) in die oksel. Dit is 'n baie ligte geval van Hidradenitis suppurativa.
References
Hidradenitis suppurativa is 'n veltoestand wat chronies is, wat aanhou terugkom en jou lewe ernstig kan beïnvloed. Dit word veroorsaak deur inflammasie in die haarfollikels, en dit lei dikwels tot bakteriële infeksies. Dokters diagnoseer dit gewoonlik deur te kyk na die soort sere wat jy het (soos knoppies, absesse of sinuskanale) , waar hulle is (gewoonlik in velvoue) , en hoe gereeld hulle terugkom en hoe lank hulle vashou.
Hidradenitis suppurativa is a chronic, recurrent, and debilitating skin condition. It is an inflammatory disorder of the follicular epithelium, but secondary bacterial infection can often occur. The diagnosis is made clinically based on typical lesions (nodules, abscesses, sinus tracts), locations (skin folds), and nature of relapses and chronicity.
Hidradenitis suppurativa is a chronic, recurrent, and debilitating skin condition. It is an inflammatory disorder of the follicular epithelium, but secondary bacterial infection can often occur. The diagnosis is made clinically based on typical lesions (nodules, abscesses, sinus tracts), locations (skin folds), and nature of relapses and chronicity.
Nie-biologiese en nie-prosedurele behandelings word algemeen alleen vir ligte siektes gebruik en kan gekombineer word met biologiese terapie en chirurgie vir matige tot ernstige siektes. Onlangse studies verskaf bykomende bewyse van doeltreffendheid vir die gebruik van kortikosteroïede wat direk in die letsels ingespuit word vir HS-opvlamsels en gelokaliseerde letsels. Verder is daar bewyse wat daarop dui dat die gebruik van tetrasikliene alleen net so effektief kan wees as om klindamisien met rifampisien te kombineer.
Non-biologic and non-procedural treatments are often used as monotherapy for mild disease and can be used in conjunction with biologic therapy and surgery for moderate to severe disease. Recent studies highlighted in this review add support for the use of intralesional corticosteroids for HS flares and localized lesions, and there is evidence that monotherapy with tetracyclines may be as effective as the clindamycin/rifampicin combination.
Non-biologic and non-procedural treatments are often used as monotherapy for mild disease and can be used in conjunction with biologic therapy and surgery for moderate to severe disease. Recent studies highlighted in this review add support for the use of intralesional corticosteroids for HS flares and localized lesions, and there is evidence that monotherapy with tetracyclines may be as effective as the clindamycin/rifampicin combination.
Baie behandelings word gebruik vir hidradenitis suppurativa, insluitend antibiotika, retinoïede, antiandrogene, immuunonderdrukkende middels, anti-inflammatoriese medikasie en radioterapie vir vroeë letsels. Die mees aanbevole behandelings is adalimumab en laserterapie. Chirurgie, hetsy eenvoudige uitsny of volledige plaaslike uitsny met veloorplanting, is die voorkeuropsie vir ernstige, gevorderde gevalle wat nie goed op ander behandelings reageer nie.
Many treatments are used for hidradenitis suppurativa, including antibiotics, retinoids, antiandrogens, immune-suppressing drugs, anti-inflammatory medications, and radiotherapy for early lesions. The top recommended treatments are adalimumab and laser therapy. Surgery, either simple excision or complete local excision with skin grafting, is the preferred option for severe, advanced cases that don't respond well to other treatments.
Many treatments are used for hidradenitis suppurativa, including antibiotics, retinoids, antiandrogens, immune-suppressing drugs, anti-inflammatory medications, and radiotherapy for early lesions. The top recommended treatments are adalimumab and laser therapy. Surgery, either simple excision or complete local excision with skin grafting, is the preferred option for severe, advanced cases that don't respond well to other treatments.
Die presiese oorsaak is gewoonlik onduidelik, maar daar word geglo dat dit 'n kombinasie van genetiese en omgewingsfaktore behels. Ongeveer 'n derde van mense met die siekte het 'n aangetaste familielid. Ander risikofaktore sluit in vetsug en rook. Die toestand word nie veroorsaak deur 'n infeksie, swak higiëne nie.
Geen genesing is bekend nie. Om die letsels oop te sny om dit te laat dreineer, lei nie tot noemenswaardige voordeel nie. Terwyl antibiotika algemeen gebruik word, is bewyse vir die gebruik daarvan swak. Immuunonderdrukkende medikasie kan ook probeer word. In diegene met meer ernstige siektes, kan laserterapie of chirurgie om die aangetaste vel te verwyder lewensvatbaar wees. Selde kan 'n velletsel in velkanker ontwikkel.
As ligte gevalle van hidradenitis suppurativa ingesluit word, is die skatting van die frekwensie daarvan 1-4% van die bevolking. Vroue is drie keer meer geneig om daarmee gediagnoseer te word as mans. Aanvang is tipies in jong volwassenheid.