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Juvenile xanthogranuloma (JXG) is 'n redelik algemene toestand en die mees algemene tipe non-Langerhans cell histiocytic disorder by kinders. In ongeveer 75% van die gevalle verskyn hierdie letsels binne die eerste lewensjaar, en meer as 15-20% van pasiënte het dit vanaf geboorte. Alhoewel dit skaars is by volwassenes, kom JXG gewoonlik die meeste voor by mense in hul laat twintigs tot dertigs, en die meeste volwasse pasiënte het net een letsel. Klinies kom dit voor as enkele of meervoudige geel-oranje-bruin ferm knoppe of knoppe, hoofsaaklik op die gesig, nek en bolyf. Orale letsels is ongewoon, maar kan as 'n geel knop aan die kante van die tong of elders in die mond voorkom, wat moontlik tot maagsere en bloeding kan lei. Velletsels veroorsaak gewoonlik nie simptome nie en is geneig om oor 'n paar jaar vanself weg te gaan. Alhoewel dit skaars is, is okulêre betrokkenheid die mees algemene probleem buite die vel, gevolg deur longbetrokkenheid. Ocular JXG affekteer tipies net een oog en kom by minder as 0. 5 % van pasiënte voor, alhoewel ongeveer 40% van diegene met okulêre betrokkenheid ook veelvuldige velletsels het wanneer hulle gediagnoseer word.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.

Juvenile xanthogranulomas (JXGs) is ongewone, goedaardige siektes wat deel is van 'n groter kategorie van non-Langerhans cell histiocytoses. Hulle verskyn tipies as een of meer rooi of gelerige knoppe, wat dikwels op die kop of nek voorkom. Die meeste JXG's ontwikkel óf by geboorte óf binne die eerste jaar van die lewe. Alhoewel dit ongewoon is, kan dit soms areas buite die vel affekteer, met oogbetrokkenheid wat volgens bestaande literatuur iets is om na op te let. Oor die algemeen gaan JXG's op die vel vanself weg en het gewoonlik nie behandeling nodig nie.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.