Onychomysosis - Toonnael Swam
☆ In die 2022 Stiftung Warentest-resultate van Duitsland was verbruikerstevredenheid met ModelDerm net effens laer as met betaalde telemedisyne-konsultasies.
'n Toonnael aangetas deur Toonnael Swam (Onychomysosis)
'n Persoon se voet met 'n swam naelinfeksie tien weke in 'n kursus terbinafien orale medikasie. Let op die band van gesonde naelgroei agter die oorblywende besmette naels.
References
Sistemiese antifungale middels is die doeltreffendste behandeling. Meta-ontledings toon mikotiese genesingsyfers soos volg: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48% . Gepaardgaande spykerdebridement verhoog genesingsyfers verder. Aktuele terapie met ciclopirox is minder effektief; dit het 'n druipsyfer van meer as 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Onychomycosis is 'n swaminfeksie wat die naels aantas. Wanneer dit deur dermatofiete veroorsaak word, word dit tinea unguium genoem. Onychomycosis sluit infeksies in wat veroorsaak word deur dermatofiete, giste en vorm. 'n Spykerprobleem wat nie deur 'n swaminfeksie veroorsaak word nie, word 'n nail dystrophy genoem. Alhoewel dit beide vingernaels en toonnaels kan beïnvloed, is toonnael onychomycosis meer algemeen. Hierdie artikel bespreek verskeie aspekte van toonnael onychomycosis, soos die impak daarvan, kliniese tipes, stadiums, diagnose en behandeling. Alhoewel dit nie lewensgevaarlik is nie, kan onychomycosis lei tot ernstige komplikasies soos sellulitis, sepsis, beeninfeksie, weefselskade en spykerverlies.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Terbinafine is 'n medikasie wat swaminfeksies beveg deur squaleenepoksidase te blokkeer. Dit is effektief teen baie soorte velswamme en is goedgekeur vir die behandeling van naelswam wanneer dit mondelings ingeneem word. Terwyl die meeste newe-effekte soos hoofpyne en maagprobleme gering is en vanself verdwyn, kan veranderinge in smaak (disgeusie) wissel van lig tot ernstig, wat soms tot gewigsverlies lei. Permanente smaakveranderinge is skaars, maar is aangemeld.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Onychomycosis is 'n swaminfeksie wat naels aantas. Ongeveer 90% van toonnaelinfeksies en 75% van vingernaelinfeksies word deur swamme (Trichophyton mentagrophytes, Trichophyton rubrum) veroorsaak. Simptome sluit in spykerverkleuring, verdikking, skeiding van die spykerbed en oorgroei. Behandeling behels gewoonlik orale medikasie soos terbinafien of itrakonasool, met aktuele behandelings wat 'n opsie is vir ligte tot matige gevalle.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Die antifungale medikasie terbinafien wat deur die mond geneem word, blyk die doeltreffendste te wees, maar terbinafien word geassosieer met die newe-effek van lewer.
toonnael swam (onychomysosis) kom voor in ongeveer 10 persent van die volwasse bevolking, met ouer mense wat meer gereeld geraak word. Mans word meer dikwels as wyfies aangetas. toonnael swam (onychomysosis) verteenwoordig ongeveer die helfte van naelsiekte. Dit beteken dat die misvorming van die toonnaels ook van ander oorsake as onychomycosis kan kom.
○ Behandeling ― OTC-dwelms
Dit is moeilik om onychomycosis met aktuele medikasie te behandel omdat dit moeilik is vir dwelms om die verdikte toonnaels binne te dring.
#Ketoconazole
#Clotrimazole
#Miconazole
#Terbinafine
#Butenafine [Lotrimin]
#Tolnaftate
○ Behandeling
Langtermynbehandeling word gewoonlik vereis totdat die besmette toonnael heeltemal verwyder is.
#Terbinafine (oral)
#Itraconazole
#Efinaconazole lacquer [Jublia]
#Ciclopirox lacquer