Panniculitis - Pannikulitis
☆ In die 2022 Stiftung Warentest-resultate van Duitsland was verbruikerstevredenheid met ModelDerm net effens laer as met betaalde telemedisyne-konsultasies.
Tuberkulose is een van die beduidende oorsake.
References
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis vorm 'n heterogene groep inflammatoriese siektes wat die onderhuidse vetweefsel behels. Hierdie afwykings is skaars by kinders. Die pannikulitis kan die primêre proses wees in 'n sistemiese versteuring of 'n sekondêre proses wat voortspruit uit infeksie, trauma of blootstelling aan medikasie. Die meeste tipes pannikulitis het dieselfde kliniese voorkoms (ongeag die etiologie) , met sagte, eritematiese subkutane nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , inflammasie van die onderhuidse vet, kom gewoonlik voor met inflammatoriese knoppies. Erythema nodosum (EN) is klinies die mees algemene vorm van pannikulitis. Terwyl tot 55% van EN as idiopaties beskou word, sluit die mees algemene oorsake infeksies, dwelms, sistemiese siektes soos sarkoïdose en inflammatoriese dermsiekte, swangerskap en kwaadaardigheid in. EN kom tipies voor in die tiener- en 20's, en word meer algemeen by vroue gesien. Dit word dikwels voorafgegaan deur 'n nie-spesifieke prodroom van een tot drie weke, wat koors, malaise en simptome van 'n boonste lugweginfeksie kan insluit. Kutane letsels volg dan, tipies gelokaliseer op die ekstensoraspek van die ledemate. Die letsels is pynlik, afgerond of ovaal, effens verhewe, nie-ulceratiewe rooi nodules. Die presiese patogenese van EN word nie verstaan nie, alhoewel dit vermoedelik voortspruit uit afsetting van immuunkomplekse in die venules van die septae in onderhuidse vet, wat 'n neutrofiele pannikulitis veroorsaak. Selfs sonder spesifieke terapie vir 'n veroorsakende toestand, word EN in die meeste gevalle sonder behandeling opgelos.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
"Erythema nodosum" is 'n vorm van pannikulitis (panniculitis) wat gekenmerk word deur sagte rooi knoppies, 1–10 cm, wat geassosieer word met sistemiese simptome insluitend koors, malaise en gewrigspyn. Nodules kan oor 'n tydperk van 2-6 weke sak sonder om ulserasie of littekens te vorm. Erythema nodosum word geassosieer met infeksies, insluitend hepatitis C, EBV en tuberkulose, swangerskap, nie-Hodgkin limfoom en pankreaskanker.