Staphylococcal scalded skin syndromehttps://en.wikipedia.org/wiki/Staphylococcal_scalded_skin_syndrome
Staphylococcal scalded skin syndrome (SSSS) is 'n dermatologiese toestand wat deur Staphylococcus aureus veroorsaak word. Die siekte kom voor met die wydverspreide vorming van vloeistofgevulde blase wat dunwandig is en maklik skeur. Staphylococcal scalded skin syndrome sluit dikwels 'n wydverspreide pynlike eritroderma in, wat dikwels die gesig, luier en ander intertriginous areas insluit. Uitgebreide areas van afskilfering kan teenwoordig wees. Korsvorming en skeuring rondom die mond word in die vroeë fase gesien. Anders as toksiese epidermale nekrolise, word die slymvliese nie aangetas in die staphylococcal scalded skin syndrome nie. Dit is die algemeenste by kinders onder 6 jaar.

Die sindroom word geïnduseer deur epidermolitiese eksotoksiene (exfoliatin)A en B, wat deur S. aureus vrygestel word. Die prognose van staphylococcal scalded skin syndrome by kinders is uitstekend, met volledige oplossing binne 10 dae van behandeling, en sonder noemenswaardige littekens. Staphylococcal scalded skin syndrome moet egter versigtig onderskei word van toksiese epidermale nekrolise, wat 'n swak prognose dra.

Diagnose en behandeling
Verkeerde diagnose as ekseemletsels soos atopiese dermatitis, en toediening van steroïedsalf vererger letsels. Soek asseblief mediese hulp so gou as moontlik terwyl jy antibiotiese salf aansmeer.

#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)
☆ In die 2022 Stiftung Warentest-resultate van Duitsland was verbruikerstevredenheid met ModelDerm net effens laer as met betaalde telemedisyne-konsultasies.
  • 'n Baba met Staphylococcal scalded skin syndrome
  • Dit is 'n kenmerkende kenmerk van abortive 4S met pustels op die nek.
  • Eriteem en skubbe is teenwoordig rondom die mond en oë. Dit kan lyk soos swak higiëne by babas.
References Staphylococcal Scalded Skin Syndrome 28846262 
NIH
Staphylococcal Scalded Skin Syndrome is 'n toestand waar die vel wegval as gevolg van gifstowwe wat deur sekere tipes Staphylococcus-bakterieë geproduseer word. Dit is ongewoon by kinders ouer as ses. Dit kan ook voorkom by volwassenes met verswakte immuunstelsels of ernstige nierprobleme. Die belangrikste kenmerk is uitgebreide velskil na ontsteking. Erns wissel van 'n paar blase tot wydverspreide velverlies, wat ernstige dalings in liggaamstemperatuur en onstabiliteit in bloeddruk kan veroorsaak.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
 Staphylococcal Scalded Skin Syndrome and Bullous Impetigo 34833375 
NIH
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
 Staphylococcal Scalded Skin Syndrome in a Ten-Month-Old Male - Case reports 35989790 
NIH
’n Seuntjie van 10 maande het met ’n loopneus ingekom en nie lekker geëet nie. Dokters het gesê dit was 'n boonste lugweginfeksie. Twee dae later het hy teruggekom omdat hy nie beter geword het nie en nuwe probleme soos geswelde gesig en geïrriteerde vel om die mond gehad het. Oor die volgende twee dae het die seun erger geword. Sy arms en bene het opgeswel en sy vel het begin afkom. Terug by die hospitaal het die dokters 'n rooi uitslag op sy gesig en in die voue van sy vel opgemerk, wat geblanser het wanneer dit aangeraak word. Hulle het hom met staphylococcal scalded skin syndrome (SSSS) gediagnoseer en hom deur 'n aar met antibiotika begin.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
 Staphylococcal scalded skin syndrome - Case reports 23761500 
NIH
’n 2-jarige meisie het opgedaag met ’n uitslag oor haar hele lyf wat oor 48 uur ontwikkel het, ná insekbyte op haar gesig die vorige dag. Tydens ondersoek het sy 'n wydverspreide uitslag gehad wat bestaan ​​uit klein knoppe wat saamgesmelt het, en wanneer dit liggies gevryf is, het haar vel tekens van Nikolsky-teken getoon. Daar was geen tekens van die uitslag wat haar slymvliese aantas nie. Toetse op haar bloed het geen tekens van infeksie getoon nie.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.