Acne - ብጉር
☆ እ.ኤ.አ. በ 2022 ከጀርመን የስቲፍቱንግ ዋረንቴስት ውጤቶች ፣ በሞዴልደርም የተገልጋዮች እርካታ ከሚከፈልባቸው የቴሌሜዲኬን ምክሮች በትንሹ ያነሰ ነበር።
ብጉር በቶርሶ አካባቢ። የጣን እና የጀርባው የላይኛው ክፍል የብጉር ቦታዎች ናቸው.
References
በዩናይትድ ስቴትስ ውስጥ በጣም የተለመደ የቆዳ በሽታ የሆነው ብጉር የማያቋርጥ እብጠት የቆዳ ችግር ነው። ሕክምናው ለብጉር መንስኤ የሆኑትን አራት ዋና ዋና ጉዳዮችን ለመፍታት ያለመ ነው፡- ከመጠን ያለፈ የቅባት ምርት፣ የቆዳ ሕዋስ መገንባት፣ ፕሮፒዮኒባክቴሪየም አክነስ ቅኝ ግዛት እና እብጠት። ወቅታዊ ሬቲኖይዶች እብጠትን በሚወስዱበት ጊዜ ኮሜዶኖችን በመከላከል እና በመቀነስ ሁለቱንም እብጠት እና እብጠት ያልሆኑ ጉዳቶችን በብቃት ይቆጣጠራሉ። ቤንዞይል ፐሮአክሳይድ በመድሃኒት ውስጥ የሚገኝ፣ የባክቴሪያን የመቋቋም አቅም ሳያሳድግ የባክቴሪያ መድኃኒት ነው። የአካባቢ እና የአፍ ውስጥ አንቲባዮቲኮች ብቻቸውን ሲሰሩ, ከአካባቢያዊ ሬቲኖይድ ጋር በማጣመር ውጤታማነታቸውን ያሳድጋል. ቤንዞይል ፐሮክሳይድ ወደ አንቲባዮቲክ ሕክምና መጨመር የባክቴሪያዎችን የመቋቋም እድልን ይቀንሳል. ለከባድ እና ግትር ብጉር የተፈቀደው የአፍ ኢሶትሬቲኖይን በ iPLEDGE ፕሮግራም ይተላለፋል።
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
የተለመዱ የብጉር ሕክምናዎች benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents ያካትታሉ። የአፍ ውስጥ አንቲባዮቲኮች ለረጅም ጊዜ የብጉር ሕክምና ቁልፍ አካል ናቸው, በተለይም ከመካከለኛ እስከ ከባድ ጉዳዮች. ከአካባቢያዊ ሬቲኖይድ እና ቢፒ ጋር ሲጠቀሙ በተሻለ ሁኔታ ይሰራሉ። Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin ሁሉም የውጤታማነት ማረጋገጫ አሳይተዋል።
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
አክኔን ለማከም ወቅታዊ ሬቲኖይድ ሁልጊዜ ይመከራል። ሥርዓታዊ ወይም ወቅታዊ አንቲባዮቲኮችን ሲጠቀሙ ከቤንዞይል ፐሮክሳይድ እና ሬቲኖይድ ጋር መቀላቀል አስፈላጊ ነው ነገርግን እስከ 12 ሳምንታት ብቻ። ለሌሎች ሕክምናዎች ምላሽ ላልሰጡ ከባድ የብጉር ጉዳዮች Isotretinoin የተጠበቀ ነው። እንደ ሌዘር ቴራፒ እና ኬሚካላዊ ልጣጭ እንዲሁም እንደ የተጣራ የንብ መርዝ እና የተወሰኑ አመጋገቦችን ላሉ አካላዊ ሕክምናዎች አንዳንድ ማስረጃዎች ቢኖሩም ውጤታማነታቸው አሁንም እርግጠኛ አይደለም።
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
የተለያዩ ምግቦች በታካሚዎች ላይ ብጉር ላይ እንዴት እንደሚጎዱ በርካታ ጥናቶች ተመልክተዋል. ዝቅተኛ ግሊዝሚክ ሸክም ያላቸውን ምግቦች የሚመገቡ ብጉር ያለባቸው ሰዎች ከፍ ያለ ግሊዝሚክሚክ ሸክም ያላቸውን ምግቦች ከሚመገቡት ጋር ሲነፃፀሩ አነስተኛ የብጉር ነጠብጣቦች እንደሚኖራቸው አረጋግጠዋል። የወተት ተዋጽኦዎች ከብጉር ጋር በተያያዘም ጥናት ተደርጎባቸዋል። በወተት ውስጥ ያሉ አንዳንድ ፕሮቲኖች ከስብ ወይም ከአጠቃላይ የወተት ይዘት የበለጠ ለብጉር ሊያበረክቱ የሚችሉ ይመስላል። ሌሎች ጥናቶች በኦሜጋ -3 ፋቲ አሲድ እና γ-linoleic አሲድ ላይ ያተኮሩ ናቸው። አክኔ ያለባቸው ሰዎች እነዚህን የሰባ አሲዶች አወሳሰድ ለመጨመር ብዙ ዓሳ እና ጤናማ ዘይቶችን በመመገብ ሊጠቀሙ እንደሚችሉ ይጠቁማል። በፕሮባዮቲክስ ላይ በቅርብ የተደረጉ ጥናቶች ተስፋ ሰጪ ውጤቶችን ያሳያሉ, ነገር ግን እነዚህን ቀደምት ግኝቶች ለማረጋገጥ ተጨማሪ ምርምር ያስፈልጋል.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
በሁለቱም ፆታዎች ውስጥ አንድሮጅንስ የሚባሉት ሆርሞኖች የሰበታ ምርትን በመጨመር የስርአቱ አካል ሆነው ይታያሉ። ሌላው የተለመደ ምክንያት በቆዳው ላይ የሚገኘው የኩቲባክቴሪየም acnes ባክቴሪያ ከመጠን በላይ መጨመር ነው.
እንደ አዜላይክ አሲድ፣ ቤንዞይል ፐሮክሳይድ እና ሳሊሲሊክ አሲድ ባሉ ቆዳዎች ላይ በቀጥታ የሚተገበሩ ህክምናዎች በብዛት ጥቅም ላይ ይውላሉ። አንቲባዮቲኮች እና ሬቲኖይዶች በቆዳው ላይ ተጭነው ለቆዳ ህክምና በአፍ የሚወሰዱ ቀመሮች ይገኛሉ። ይሁን እንጂ በኣንቲባዮቲክ ሕክምና ምክንያት አንቲባዮቲክን የመቋቋም ችሎታ ሊዳብር ይችላል. ብዙ አይነት የወሊድ መከላከያ ክኒኖች በሴቶች ላይ ብጉርን ለመከላከል ይረዳሉ. ኢሶትሬቲኖይንን በመጠቀም የብጉር ሕክምና ቀደም ብሎ እና ኃይለኛ ሕክምና በግለሰቦች ላይ የረዥም ጊዜ ውስብስብነትን ለመቀነስ ጠቃሚ ሊሆን ይችላል።
○ ህክምና
የአዳፓሊን ጄል በሰፊው ጥቅም ላይ ሊውል ይችላል, ምክንያቱም የሴብሊክን ፈሳሽ በመጨፍለቅ እና በተደጋጋሚ ብጉር መከሰትን ለመግታት ተጽእኖ ስላለው ነው. Adapalene gel መጀመሪያ ላይ ከመጠን በላይ ከተተገበረ ቆዳውን ሊያበሳጭ ይችላል. በሌላ በኩል ቤንዞይል ፐሮክሳይድ እና አዜላይክ አሲድ በተንቆጠቆጡ ብጉር ቦታዎች ላይ ጥቅም ላይ ሊውሉ ይችላሉ ምክንያቱም እብጠትን ለመቋቋም ይረዳሉ. በአጠቃላይ ውጤቱን ለማየት ለ 1 ወር ወይም ከዚያ በላይ የረጅም ጊዜ ህክምና ያስፈልጋል.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction