ተጨማሪ መረጃ ― አማርኛ

Cutaneous angiofibromas በተለያዩ የሰውነት ክፍሎች ላይ ሊታይ ይችላል። ፊት ላይ ብዙውን ጊዜ ፋይበርስ ፓፑልስ ወይም አድኖማ ሴባሲየም በመባል ይታወቃሉ; በወንድ ብልት ላይ pearly penile papules ይባላሉ; በምስማር ስር, ፔሪየንጉዋል angiofibromas ወይም Koenen ዕጢዎች ይባላሉ; እና በአፍ ውስጥ, የአፍ ውስጥ ፋይብሮማስ ተብለው ይጠራሉ. የፊት angiofibromas የ tuberous sclerosis (TS) በቆዳ፣ በኩላሊት፣ በልብ፣ በአንጎል እና በሳንባ ላይ በዘር የሚተላለፍ በሽታ ዋነኛ ባህሪ ነው። በሕፃንነታቸው ወይም በጉልምስና ዕድሜ ላይ ባሉ ሰዎች ፊት ላይ ብዙውን ጊዜ የቲ. ኤስ. ሶስት ወይም ከዚያ በላይ የፊት angiofibromas ወይም ሁለት ወይም ከዚያ በላይ ፔሪየንጉዋል angiofibromas መኖሩ ቲኤስን ለመመርመር ትልቅ ጠቀሜታ አለው። በተጨማሪም, በርካታ የፊት angiofibromas በሁኔታዎች (multiple endocrine neoplasia type 1 (MEN-1) እና Birt-Hogg-Dubé syndrome) ውስጥ ሊኖሩ ይችላሉ. Pearly penile papules በወንድ ብልት ክሮናል ኅዳግ እና ሰልከስ አጠገብ ይገኛሉ። ያልተገረዙ ወንዶች ላይ በብዛት የሚታዩ ቋሚ፣ ህመም የሌላቸው እብጠቶች ናቸው።
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.