Dysplastic nevus
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እ.ኤ.አ. በ 2022 ከጀርመን የስቲፍቱንግ ዋረንቴስት ውጤቶች ፣ በሞዴልደርም የተገልጋዮች እርካታ ከሚከፈልባቸው የቴሌሜዲኬን ምክሮች በትንሹ ያነሰ ነበር።
እ.ኤ.አ. በ 2022 ከጀርመን የስቲፍቱንግ ዋረንቴስት ውጤቶች ፣ በሞዴልደርም የተገልጋዮች እርካታ ከሚከፈልባቸው የቴሌሜዲኬን ምክሮች በትንሹ ያነሰ ነበር።
Dysplastic nevi ― ባዮፕሲ ለምዕራባዊዎች ይመከራል።
relevance score : -100.0%
ReferencesDysplastic nevus፣ በተጨማሪም ኤቲፒካል ወይም ክላርክ ኔቩስ በመባል የሚታወቀው፣ በቆዳ ህክምና ላይ ክርክሮችን አስነሳል። ዶክተሮች ያልተለመዱ ሊመስሉ ስለሚችሉ እና ለሜላኖማ ስጋት ስለሚፈጥሩ፣ ብዙውን ጊዜ እነዚህን ሞሎች ባዮፕሲ ያደርጋሉ።
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi፣ በተጨማሪም ኤቲፒካል ወይም ክላርክ ኔቪ በመባል የሚታወቀው፣ አንዳንድ ጊዜ ወደ melanoma ሊያመራ ይችላል። 36% የmelanoma በ dysplastic nevi አቅራቢያ ይገኛሉ። dysplastic nevus ወደ melanoma ሊለወጥ እንደሚችል የሚያሳዩ ምልክቶች ያልተስተካከለ ቅርጽ፣ ተጨማሪ የቀለም ለውጦች ወይም ግራጫማ ቀለም ናቸው። እነዚህ ካንሰሮች ብዙውን ጊዜ በወጣት ዕድሜ (በሰላሳዎቹ አጋማሽ አካባቢ) ይከሰታሉ፣ ብዙ ሊሆኑ ይችላሉ፣ እና ብዙ ጊዜ ግንዱ ላይ ይገኛሉ። በዘረመል፣ dysplastic nevi በ benign nevi እና melanoma መካከል ናቸው። ነገር ግን ከ20% እስከ 30% የሚሆኑ melanomaዎች ከነባር ኔቪ የሚመጡ ናቸው።
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
ሜላኖማ በቆዳ ቀለም ተጠያቂ የሆነ ሜላኖይተስ ሴሎች ካንሰር ሲሆን፣ የሚፈጠር ዕጢ ዓይነት ነው። ሜላኖይተስ የሚመነጨው ከነርቭ ክሬስት ነው። ይህ ማለት ሜላኖማ በቆዳ ላይ ብቻ ሳይሆን፣ እንደ ጨጓራ፣ ትራክት እና አንጎል ያሉት ሌሎች የነርቭ ሴሎች በሚፈልሱባቸው አካባቢዎችም ሊደርሱ ይችላል። በቅድመ-ደረጃ ሜሎኖማ (ደረጃ 0) ለታካሚዎች የመዳን ደረጃ 97% እስከ ደረጃ ከፍ ይሆናል፤ ከፍተኛ ደረጃ (ደረጃ IV) ያሉት በሽታዎች ደግሞ ወደ 10% ይቀንሳሉ።
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ የካንሰር አደጋ
በዩናይትድ ስቴትስ ውስጥ ካውካሲያን ግለሰቦች ላይ እንደሚታየው፣ dysplastic nevi ያላቸው ሰዎች ከ10% በላይ የሜላኖማ ዕድል አላቸው። በተባባሪ በኩል፣ ምንም ዓይነት ዲስፕላስቲክ ኔቪ የሌለው ሰው ከ1% በታች የሜላኖማ ዕድል አለው፣ ይህም ከፍተኛ ነው።
○ ጥንቃቄ ዲስፕላስቲክ nevi
ሜላኖማን (melanoma) ለመከላከል (የሚወገድ ያልተለመደ ኔቪን በመለየት) ወይም ነባር እጢዎችን ቀደም ብሎ ለማወቅ የቆዳ ራስን መምረጥ ይመከራል። የቆዳ ካንሰር ወይም ብዙ ያልተለመደ ኔቪ ያላቸው ሰዎች ቢያንስ በዓመት አንድ ጊዜ የቆዳ ህክምና ባለሙያን ማየት እና ሜላኖማ እንዳይፈጠር ማድረግ አለባቸው።
አህጽሮተ ቃል [ABCDE] የጤና እንክብካቤ አቅራቢዎችን እና ተለዋዋጭ ሰዎችን የሜላኖማ ዋና ባህሪዎችን እንዲያስታውሱ ለማግዘት ጠቃሚ ነው። እንደ አለመታደል ሆኖ በተለምዶ ብዙ ሴቦርሬይክ keratoses፣ አንዳንድ lentigo senilis እና ኪንታሮት ሊኖሩ ይችላሉ፣ ነገር ግን እነዚህ [ABCDE] ባህሪዎች ከሜላኖማ ይለያሉ አይችሉም።
○ [ABCDE]
Asymmetrical: ተመጣጣኝ ያልሆነ የቆዳ ጉዳት።
Border: የቁስሉ ድንበር መደበኛ ያልሆነ።
Color: ሜላኖማ ብዙውን ጊዜ ተለዋዋጭ ያልሆኑ ቀለሞችን አሳያል።
Diameter: ከ6 ሚሊሜትር በላይ የሆነ ኔቪ ከትንሽ ኔቪ ይልቅ ሜላኖማ የሚሆን ዕድል ከፍተናል።
Evolution: የኔቪ ወይም የቁስሉ ዝግመተ ለውጥ (ለውጥ) ቁስሉ አደገኛ እየሆነ መሄዱን ይጠቁማል።