Herpes simplex - ሄርፕስ ስፕሌክስ
☆ እ.ኤ.አ. በ 2022 ከጀርመን የስቲፍቱንግ ዋረንቴስት ውጤቶች ፣ በሞዴልደርም የተገልጋዮች እርካታ ከሚከፈልባቸው የቴሌሜዲኬን ምክሮች በትንሹ ያነሰ ነበር።
Herpes simplex ከንፈር ላይ.
ሄርፕስ ስፕሌክስ (Herpes simplex) ― የሄርፒስ ሲምፕሌክስ በጣቶች ላይ የሚከሰት ኢንፌክሽን ከአዋቂዎች ይልቅ በትናንሽ ልጆች ላይ በብዛት ይታያል።
References
HSV-1 ኢንፌክሽን በኤፒተልየል ሴሎች የመጀመሪያ ደረጃ ኢንፌክሽን አማካኝነት ያልፋል፣ በመቀጠልም መዘግየት፣ በተለይም በነርቭ ሴሎች እና እንደገና እንዲነቃቁ ያደርጋል። HSV-1 በዋነኛነት በአፍ እና በብልት ማኮስ ላይ የመጀመሪያ እና ተደጋጋሚ የቬሲኩላር ፍንዳታዎችን ያስከትላል። የእሱ መገለጫዎች ከኦሮላቢያን ሄርፒስ እስከ የተለያዩ ሁኔታዎች እንደ ሄርፔቲክ ፎሊኩላይትስ፣ የቆዳ ኢንፌክሽን፣ የአይን ተሳትፎ እና እንደ ሄርፒስ ኢንሴፈላላይትስ ያሉ ከባድ ጉዳዮችን ያጠቃልላል። የፀረ-ቫይረስ ሕክምና የ HSV ኢንፌክሽንን ለመቆጣጠር ይረዳል.
Herpes simplex virus type 1 (HSV-1) is a member of the Alphaherpesviridae subfamily. Its structure is composed of linear dsDNA, an icosahedral capsid that is 100 to 110 nm in diameter, with a spikey envelope. In general, the pathogenesis of HSV-1 infection follows a cycle of primary infection of epithelial cells, latency primarily in neurons, and reactivation. HSV-1 is responsible for establishing primary and recurrent vesicular eruptions, primarily in the orolabial and genital mucosa. HSV-1 infection has a wide variety of presentations, including orolabial herpes, herpetic sycosis (HSV folliculitis), herpes gladiatorum, herpetic whitlow, ocular HSV infection, herpes encephalitis, Kaposi varicelliform eruption (eczema herpeticum), and severe or chronic HSV infection. Antiviral therapy limits the course of HSV infection.
Herpes simplex virus type 1 (HSV-1) is a member of the Alphaherpesviridae subfamily. Its structure is composed of linear dsDNA, an icosahedral capsid that is 100 to 110 nm in diameter, with a spikey envelope. In general, the pathogenesis of HSV-1 infection follows a cycle of primary infection of epithelial cells, latency primarily in neurons, and reactivation. HSV-1 is responsible for establishing primary and recurrent vesicular eruptions, primarily in the orolabial and genital mucosa. HSV-1 infection has a wide variety of presentations, including orolabial herpes, herpetic sycosis (HSV folliculitis), herpes gladiatorum, herpetic whitlow, ocular HSV infection, herpes encephalitis, Kaposi varicelliform eruption (eczema herpeticum), and severe or chronic HSV infection. Antiviral therapy limits the course of HSV infection.
Herpes simplex virus type 2 (HSV-2) የተስፋፋ ኢንፌክሽን ሲሆን እድሜያቸው 12 እና ከዚያ በላይ የሆኑ 22% የሚሆኑ ጎልማሶችን የሚያጠቃ ሲሆን በአጠቃላይ በዩናይትድ ስቴትስ 45 ሚሊዮን ጎልማሶችን ያጠቃልላል። HSV-1 በተለምዶ የአፍ ውስጥ ቁስሎችን የሚያመጣ ቢሆንም፣ ወደ ብልት ቁስሎችም ሊመራ ይችላል። ሆኖም ግን, ታካሚዎች የጾታ ብልትን ሲጎዱ, HSV-2 አብዛኛውን ጊዜ ዋናው ጭንቀት ነው. የ HSV-2 ወረርሽኞች ምልክቶች እንደ ብልት ማሳከክ እና ብስጭት ያሉ ምልክቶች ብዙ ጊዜ ግልጽ ያልሆኑ ናቸው ይህም ምርመራን እና ህክምናን ሊያዘገይ ይችላል. ይህ መዘግየት ያልተበከሉ ሰዎች ተጨማሪ ስርጭትን ሊያስከትል ይችላል.
Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present with genital lesions. Despite this, most outbreaks of the infection will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.
Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present with genital lesions. Despite this, most outbreaks of the infection will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.
Herpes simplex virus (HSV) በጉርምስና ዕድሜ ላይ ባሉ ወጣቶች እና ጎልማሶች ላይ እንደ ብልት ሄርፒስ እና ጉንፋን ያሉ ኢንፌክሽኖችን በብዛት ያስከትላል። በመጀመሪያዎቹ 4-6 ሳምንታት ውስጥ ኤችኤስቪ ጨቅላ ህጻን ሲያጠቃ ከባድ መዘዝ ያለው ከባድ ህመም ሊያስከትል ይችላል። አዲስ የተወለደውን የ HSV ኢንፌክሽን በፍጥነት መመርመር በሽታው እንዳይባባስ ለመከላከል, የነርቭ ጉዳዮችን (ሞትንም ጭምር) ለመከላከል በጣም አስፈላጊ ነው.
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death.
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death.
Herpes simplex ኢንፌክሽን በጣም የተለመደ እና ከነፍሰ ጡር ሴቶች ወደ ህጻናት ሊተላለፍ ይችላል. ይህ ቫይረስ ከባድ የጤና ችግሮች ሊያስከትል አልፎ ተርፎም በተወለዱ ሕፃናት ላይ ሞት ሊያስከትል ይችላል. በእርግዝና ወቅት በራሱ ያልተለመደ ቢሆንም, ብዙውን ጊዜ በወሊድ ጊዜ ይከሰታል. እናትየው በመጨረሻዎቹ የእርግዝና እርከኖች ውስጥ ከተያዘች አደጋው ከፍተኛ ነው። ይሁን እንጂ ይህ አደጋ የፀረ-ቫይረስ መድሃኒቶችን በመጠቀም ወይም በአንዳንድ ሁኔታዎች የ C ክፍልን በመምረጥ ሊቀነስ ይችላል.
Infection with herpes simplex is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn. Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in the uterus, it occurs frequently during the transmission delivery. The greatest risk of transmission to the fetus and the newborn occurs in case of an initial maternal infection contracted in the second half of pregnancy. The risk of transmission of maternal-fetal-neonatal herpes simplex can be decreased by performing a treatment with antiviral drugs or resorting to a caesarean section in some specific cases.
Infection with herpes simplex is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn. Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in the uterus, it occurs frequently during the transmission delivery. The greatest risk of transmission to the fetus and the newborn occurs in case of an initial maternal infection contracted in the second half of pregnancy. The risk of transmission of maternal-fetal-neonatal herpes simplex can be decreased by performing a treatment with antiviral drugs or resorting to a caesarean section in some specific cases.
Herpes simplex virus (HSV) አይነት 1 እና 2 በአለም ዙሪያ ብዙ ሰዎችን ያጠቃሉ። አብዛኛውን ጊዜ ቫይረሱ በቆዳው ላይ ከተበከለ በኋላ በነርቭ ሴሎች ውስጥ ጸጥ ይላል, ነገር ግን በኋላ ላይ እንደገና እንዲነቃነቅ ሊያደርግ ይችላል, ይህም ቀዝቃዛ ቁስለት ያስከትላል. አንዳንድ ጊዜ፣ እንደ የአይን ኢንፌክሽን፣ የአንጎል ብግነት፣ ወይም አዲስ በተወለዱ ሕፃናት እና ደካማ የሰውነት መከላከል ስርአቶች ላይ ያሉ አደገኛ ሁኔታዎችን ወደመሳሰሉ ከባድ ችግሮች ይመራል። አሁን ያሉት መድሃኒቶች ኢንፌክሽኖችን ለመቆጣጠር የሚረዱ ቢሆኑም የመድሃኒት መከላከያ እና የጎንዮሽ ጉዳቶች ስጋት አሁንም አሳሳቢ ነው. ቫይረሱን በተሻለ ሁኔታ ለማጥቃት አዳዲስ መድሃኒቶች ያስፈልጉናል.
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human population. Most commonly, virus replication is limited to the epithelia and establishes latency in enervating sensory neurons, reactivating periodically to produce localized recurrent lesions. However, these viruses can also cause severe disease such as recurrent keratitis leading potentially to blindness, as well as encephalitis, and systemic disease in neonates and immunocompromised patients. Although antiviral therapy has allowed continual and substantial improvement in the management of both primary and recurrent infections, resistance to currently available drugs and long-term toxicity pose a current and future threat that should be addressed through the development of new antiviral compounds directed against new targets.
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human population. Most commonly, virus replication is limited to the epithelia and establishes latency in enervating sensory neurons, reactivating periodically to produce localized recurrent lesions. However, these viruses can also cause severe disease such as recurrent keratitis leading potentially to blindness, as well as encephalitis, and systemic disease in neonates and immunocompromised patients. Although antiviral therapy has allowed continual and substantial improvement in the management of both primary and recurrent infections, resistance to currently available drugs and long-term toxicity pose a current and future threat that should be addressed through the development of new antiviral compounds directed against new targets.
ሁለት ዓይነት የ ሄርፕስ ስፕሌክስ (herpes simplex) ቫይረስ፣ ዓይነት 1 (HSV-1) እና ዓይነት 2 (HSV-2) አሉ። HSV-1 በአፍ አካባቢ ኢንፌክሽኖችን የሚያመጣ ሲሆን HSV-2 ደግሞ የብልት ኢንፌክሽንን በብዛት ያመጣል። የሚተላለፉት ከታመመው ሰው ጋር በቀጥታ በመገናኘት ነው. የብልት ሄርፒስ በግብረ ሥጋ ግንኙነት የሚተላለፍ ኢንፌክሽን ተብሎ ይመደባል. በወሊድ ጊዜ ወደ ሕፃን ሊተላለፍ ይችላል. ከበሽታው በኋላ ቫይረሶች ከስሜታዊ ነርቮች ጋር ወደ ነርቭ ሴል አካላት ይጓጓዛሉ, እነሱም እድሜ ልክ ይኖራሉ. የመድገም መንስኤዎች የሚከተሉትን ሊያካትቱ ይችላሉ-የመከላከያ ተግባራት መቀነስ, ውጥረት እና የፀሐይ ብርሃን መጋለጥ.
በአብዛኛዎቹ ሁኔታዎች የፀረ-ቫይረስ መድሃኒቶች የሚወሰዱት የሕመም ምልክቶች ሲታዩ ብቻ ነው. በጣም በተደጋጋሚ ኢንፌክሽን ላለው ሰው በየቀኑ የፀረ-ቫይረስ መድሃኒት ሊታዘዝ ይችላል. ምንም አይነት ክትባት የለም እና የሺንግልስ ክትባት የሄርፒስ ሲምፕሌክስን አይከላከልም. እንደ አሲክሎቪር ወይም ቫላሲክሎቪር ባሉ የፀረ-ቫይረስ መድሃኒቶች የሚደረግ ሕክምና የሕመም ምልክቶችን ክብደት ይቀንሳል።
የአለም አቀፍ የHSV-1 ወይም HSV-2 ተመኖች በአዋቂዎች ከ60% እስከ 95% ናቸው። HSV-1 ብዙውን ጊዜ በልጅነት ጊዜ ይያዛል. እንደ 2003 በዓለም ዙሪያ 536 ሚሊዮን ሰዎች (16 በመቶው ህዝብ) በ HSV-2 የተያዙ ሲሆን በሴቶች እና በማደግ ላይ ባሉ ዓለም ውስጥ ካሉት የበለጠ። አብዛኛዎቹ HSV-2 ያለባቸው ሰዎች እንደተበከሉ አይገነዘቡም።
○ ህክምና ― OTC መድሃኒቶች
አረፋዎቹ በሚታዩበት ጊዜ እንደ ልጅ መሳም ያሉ ማንኛውንም አካላዊ ንክኪ ያስወግዱ፣ ምክንያቱም ግንኙነት ኢንፌክሽኑን ወደ ሌሎች ሰዎች ሊያስተላልፍ ይችላል። አልኮል ሳይጠጡ ማረፍ አለብዎት.
#Acyclovir cream