Intraepithelial carcinoma (Bowen disease)
☆ እ.ኤ.አ. በ 2022 ከጀርመን የስቲፍቱንግ ዋረንቴስት ውጤቶች ፣ በሞዴልደርም የተገልጋዮች እርካታ ከሚከፈልባቸው የቴሌሜዲኬን ምክሮች በትንሹ ያነሰ ነበር።
የተለመደ ጉዳይ - Intraepithelial carcinoma (Bowen disease) ለረጅም ጊዜ የሚቆይ የማያሳከክ ኤክማማ ተብሎ ሊታወቅ ይችላል።
References
Bowen's disease (BD) ከቆዳው ውጫዊ ክፍል (ኤፒደርሚስ) የሚጀምር የቆዳ ካንሰር አይነት ነው። በካውካሰስ ውስጥ በጣም የተለመደ ነው እና ብዙ ጊዜ ለፀሐይ ብርሃን በተጋለጡ አካባቢዎች ይከሰታል, ነገር ግን ሌላ ቦታም ሊታይ ይችላል. BD በተለምዶ እንደ ነጠላ ቁስል ይታያል. BD ብዙ ጊዜ ይበልጥ አሳሳቢ የሆነ የቆዳ ካንሰር ከመፈጠሩ በፊት እንደ የማስጠንቀቂያ ምልክት ይታያል። ቢዲ (BD) ን ለመመርመር ዶክተሮች አብዛኛውን ጊዜ የቲሹ ናሙናዎችን በአጉሊ መነጽር (ባዮፕሲ) በመመርመር ይተማመናሉ።
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease በአብዛኛው እድሜያቸው ከ60 በላይ የሆኑ ነጮችን ይጎዳል። ቁልፍ ተጋላጭነት ምክንያቶች ለረጅም ጊዜ ለፀሀይ መጋለጥ፣ የበሽታ መከላከል አቅም ማዳከም፣ የአርሴኒክ ተጋላጭነት እና የቆዳ የ HPV ኢንፌክሽን ያካትታሉ። የ HPV ዝርያዎች 16፣ 18፣ 34 እና 48 ከቦወን በሽታ ጋር የተገናኙት በብልት አካባቢ ነው። የ HPV ብልት ባልሆኑ ጉዳዮች ላይ ያለው ተሳትፎ ብዙም ግልጽ ነው።
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
ብዙውን ጊዜ በሰውነት ውስጥ በየትኛውም ቦታ ላይ እንደ ቀይ, ቅርፊት ወይም ቅርፊት ይታያል. በጣም የተለመደው ቦታ የታችኛው እግሮች ናቸው.
በተለያዩ የሕክምና አማራጮች እንደ ክሪዮቴራፒ, ማከሚያ, ካውቴሪ, የፎቶዳይናሚክ ቴራፒ, ወይም የቁስል መቆረጥ ባሉ የሕክምና አማራጮች ሊድን ይችላል.
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