ተጨማሪ መረጃ ― አማርኛ

Pigmented purpuric dermatoses (PPD) ከቆዳው በታች በሚከሰት የደም መፍሰስ ምክንያት በካፒላሪ እብጠት ምክንያት የሚታዩ የቆዳ በሽታዎች ቡድን ናቸው። ፒ. ፒ. ዲ በተለምዶ ከቀይ እስከ ወይን ጠጅ ነጠብጣቦች ይጀምራል ፣ በኋላ ሄሞሲዲሪን እንደገና ሲጠጣ ወርቃማ-ቡናማ ይሆናል።
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.

Schamberg disease በጣም የተለመደው የ pigmented purpuric dermatoses (PPDs) አይነት ሲሆን እነዚህም ሥር የሰደደ የቆዳ በሽታዎች በትናንሽ ቀይ ወይም ወይን ጠጅ ነጠብጣቦች የሚታወቁ እና የቆዳ ቀለም መጨመር (ቡናማ፣ ቀይ ወይም ቢጫ) ናቸው። ፒፒዲዎች በአምስት ዓይነቶች ይከፈላሉ፡ Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, eczematoid-like purpura of Doucas and Kapetanakis ። progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressiva, Schamberg's purpura Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, eczematoid-like purpura of Doucas and Kapetanakis በመባልም ይታወቃል። እሱ በዋነኝነት ወንዶችን ይጎዳል እና ብዙውን ጊዜ በታችኛው እግሮች ላይ ይታያል ፣ ግን በጭኑ ፣ መቀመጫዎች ፣ ግንድ ወይም ክንዶች ላይም ሊከሰት ይችላል።
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.

ለዚህ ጥናት የቆዳ ባዮፕሲ የተደረገባቸውን 38 ጨምሮ PPD ስላላቸው 113 ታካሚዎች መረጃ ተተነተነ። በጣም የተለመደው የሕክምና ዓይነት የሻምበርግ በሽታ (60. 5%) ነው. ከፒፒዲ ጋር ያሉ ሌሎች ሁኔታዎች የደም ግፊት (15. 8%) ፣ የስኳር በሽታ (10. 5%) እና ሌሎች ናቸው። የመድኃኒት ታሪክ ስታቲኖች (13. 2%) ፣ ቤታ አጋጆች (10. 5%) እና ሌሎችም አሳይተዋል። ከፒፒዲ ጋር የተገናኙ ሊሆኑ የሚችሉ ምክንያቶች የቅርብ ጊዜ የላይኛው የመተንፈሻ አካላት ኢንፌክሽን (5. 3%) ፣ ረዘም ላለ ጊዜ መቆም ወደ ከፍተኛ orthostatic ግፊት (2. 6%) እና ከባድ የአካል ብቃት እንቅስቃሴ (2. 6%) ያካትታሉ። ሕክምናው ለ 36 ታካሚዎች (94. 7%) - oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy ተሰጥቷል.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.