Acanthosis nigricans
☆ U rezultatima Stiftung Warentest-a za 2022. iz Njemačke, zadovoljstvo potrošača ModelDerm-om bilo je samo nešto niže nego s plaćenim telemedicinskim konsultacijama.
Uobičajeno je kod gojaznih ljudi.
References
Acanthosis nigricans je kožna manifestacija osnovnog stanja. Često se pojavljuje u kožnim naborima poput vrata, pazuha i prepona, izgledajući kao baršunaste tamne mrlje s nejasnim rubovima. Ovo stanje je obično povezano s dijabetesom i rezistencijom na inzulin, ali u rijetkim slučajevima može ukazivati na rak u tijelu. Može se pojaviti i zbog problema s hormonima ili zbog uzimanja određenih lijekova kao što su steroidi i kontracepcijske pilule.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans (AN) je uobičajeno stanje kože povezano s raznim zdravstvenim problemima poput inzulinske rezistencije, dijabetesa, gojaznosti, određenih karcinoma, hormonalnih problema i reakcija na lijekove. Liječenje AN fokusira se na rješavanje osnovnih zdravstvenih problema. U početku liječnici provjeravaju da li postoje znakovi sindroma inzulinske rezistencije, koji uključuje gojaznost, visok holesterol, visok krvni pritisak i dijabetes tipa 2. Doktori često propisuju topical retinoids kao prvi izbor tretmana, koji može pomoći kod zadebljanja kože. Međutim, oni možda neće u potpunosti riješiti potamnjenje kože. Druge opcije tretmana kao što je salicylic acid, podophyllin, urea, and calcipotriol također zahtijevaju čestu primjenu.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
○ Uzroci
Obično se javlja kod osoba mlađih od 40 godina, može biti genetski naslijeđen i povezan je s gojaznošću ili endokrinopatijama, kao što su hipotireoza, akromegalija, bolest policističnih jajnika, dijabetes rezistentni na inzulin ili Cushingova bolest.
○ Liječenje ― OTC lijekovi
#40% urea cream