Acne - Akne
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U rezultatima Stiftung Warentest-a za 2022. iz Njemačke, zadovoljstvo potrošača ModelDerm-om bilo je samo nešto niže nego s plaćenim telemedicinskim konsultacijama.
U rezultatima Stiftung Warentest-a za 2022. iz Njemačke, zadovoljstvo potrošača ModelDerm-om bilo je samo nešto niže nego s plaćenim telemedicinskim konsultacijama.
Akne u predjelu torza. Gornji dio trupa i leđa najčešća su područja akni.
relevance score : -100.0%
ReferencesAkne, najčešće stanje kože u Sjedinjenim Državama, predstavljaju uporni upalni problem kože. Tretman ima za cilj rješavanje četiri glavna faktora koja doprinose nastanku akni: prekomjernu proizvodnju sebuma, nakupljanje ćelija kože, kolonizaciju Propionibacterium acnes i posljedičnu upalu. Lokalni retinoidi efikasno djeluju na upalne i neupalne lezije tako što sprečavaju nastanak i smanjuju komedone, a istovremeno ublažavaju upalu. Benzoil peroksid, dostupan u slobodnoj prodaji, baktericidni je agens koji ne potiče otpornost bakterija. Iako lokalni i oralni antibiotici djeluju samostalno, njihova kombinacija s lokalnim retinoidima povećava njihovu učinkovitost. Dodavanje benzoil peroksida antibioticnoj terapiji smanjuje rizik od rezistencije bakterija. Oralni izotretinoin, odobren za teške i tvrdokorne akne, primjenjuje se kroz iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Uobičajeni lokalni tretmani za akne uključuju benzoyl peroxide (BP), salicylic acid, antibiotike, kombinacije antibiotika s BP, retinoide, kombinacije retinoida s BP ili antibiotikima, azelaic acid i sulfon‑agente. Oralni antibiotici dugo su bili ključni dio liječenja akni, posebno kod umjerenih do teških slučajeva. Najbolje djeluju kada se koriste zajedno s lokalnim retinoidom. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin i cephalexin svi su pokazali dokaz efikasnosti.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Lokalni retinoidi se uvijek preporučuju za liječenje akni. Kada koristite sistemske ili lokalne antibiotike, važno je da ih kombinujete s benzoil peroksidom i retinoidima, ali najduje 12 nedelja. Isotretinoin je rezervisan za teške slučajeve akni koji nisu reagovali na druge tretmane. Iako postoje dokazi o fizikalnim tretmanima, poput laserske terapije i hemijskog pilinga, kao i o komplementarnim pristupima, poput pročišćenog pčelinjeg otrova i određenih dijeta, njihova efikasnost još uvijek nije dokazana.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Nekoliko studija je proučavalo kako različita hrana utiče na akne kod pacijenata. Otkrili su da ljudi s aknama koji jedu hranu s niskim glikemijskim opterećenjem imaju manje aknogenih mrlja u poređenju s onima koji konzumiraju hranu s visokim glikemijskim opterećenjem. Mliječni proizvodi su također istraživani u vezi s aknama. Čini se da određeni proteini u mlijeku mogu više doprinijeti nastanku akni nego masti ili ukupni sadržaj mliječnih proizvoda. Druga istraživanja su se fokusirala na omega‑3 masne kiseline i γ‑linolnu kiselinu. To sugerira da bi osobe s aknama mogle imati koristi od veće konzumacije ribe i zdravih ulja kako bi povećale unos ovih masnih kiselina. Nedavne studije o probioticima za akne pokazuju obećavajuće rezultate, ali je potrebno više istraživanja da se ovi rani nalazi potvrde.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Čini se da hormoni poznati kao androgeni, kod oba spola, igraju ključnu ulogu u osnovnom mehanizmu, povećavajući proizvodnju sebuma. Još jedan čest faktor je pretjerani rast bakterije Cutibacterium acnes, koja je prisutna na koži.
Obično se koriste topički tretmani koji se primjenjuju direktno na zahvaćenu kožu, poput azelainske kiseline, benzoil peroksida i salicilne kiseline. Antibiotici i retinoidi dostupni su i u obliku preparata za lokalnu primjenu i oralnih oblika. Međutim, rezistencija na antibiotike može se razviti kao posljedica dugotrajne terapije. Nekoliko kontracepcijskih pilula može pomoći u sprječavanju akni kod žena. Rano i agresivno liječenje izotretinoinom može biti od pomoći za smanjenje dugoročnih komplikacija.
○ Tretman
Adapalen gel može se široko koristiti jer smanjuje lučenje sebuma i sprječava ponovni nastanak akni. Gel može iritirati kožu ako se u početku nanese previše. Benzoil peroksid i azelainska kiselina, s druge strane, mogu se primijeniti na upalna područja jer ublažavaju upalu. Općenito, potrebno je dugotrajno liječenje od mjesec dana ili duže da bi se primijetio učinak.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction