Angiofibrom (Angiofibroma) je tvrda papula, nodula ili tumoralna lezija. Angiofibromi se ponekad pogrešno dijagnosticiraju kao akne. Na njihovim lokacijama nazivaju se: 1) na licu – Fibrous papule 2) na penisu – Pearly penile papule 3) ispod nokta na ruci ili nozi – Periungual angiofibroma
Angiofibromas are small, reddish brown or even flesh-colored, smooth, shiny, 0.1 to 0.3 cm papules present over the sides of the nose and the medial portions of the cheeks. They contain fibrous tissue.
☆ AI Dermatology — Free Service U rezultatima Stiftung Warentest-a za 2022. iz Njemačke, zadovoljstvo potrošača ModelDerm-om bilo je samo nešto niže nego s plaćenim telemedicinskim konsultacijama.
Angiofibrom (Angiofibroma) izgleda slično akni. Lezije se uglavnom javljaju oko nosa.
Cutaneous angiofibromas mogu se pojaviti na različitim dijelovima tijela. Na licu su često poznati kao fibrozne papule ili adenom sebaceum; na penisu se nazivaju pearly penile papules; ispod nokta – periungualni angiofibromi ili Koenenovi tumori; a u ustima – oralni fibromi. Angiofibromi lica su istaknuta karakteristika tuberous sclerosis (TS), nasljednog poremećaja koji pogađa kožu, bubrege, srce, mozak i pluća. Obično se razvijaju na licu tokom djetinjstva ili ranog odraslog doba kod osoba s TS. Prisustvo tri ili više angiofibroma lica ili dva ili više periungualnih angiofibroma smatra se značajnim za dijagnozu TS. Dodatno, višestruki angiofibromi lica mogu se pojaviti u stanjima kao što su multiple endocrine neoplasia type 1 (MEN-1) i Birt-Hogg-Dubé syndrome. Pearly penile papules nalaze se duž koronalne ivice i brazde penisa. To su uporne, bezbolne kvržice koje se češće vide kod neobrezanih muškaraca. Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
1) na licu – Fibrous papule
2) na penisu – Pearly penile papule
3) ispod nokta na ruci ili nozi – Periungual angiofibroma