Erythema nodosum - Nodozni Eritem
☆ U rezultatima Stiftung Warentest-a za 2022. iz Njemačke, zadovoljstvo potrošača ModelDerm-om bilo je samo nešto niže nego s plaćenim telemedicinskim konsultacijama.
Izgleda kao bolni eritematozni čvor na nozi.
References
Erythema nodosum je najčešći tip panikulitisa, karakteriziran bolnim crvenim čvorovima, koji se uglavnom nalaze na potkoljenicama. Njegov tačan uzrok ostaje nepoznat, ali čini se da je rezultat pretjeranog odgovora na različite okidače. Iako je njegovo porijeklo često neizvjesno, bitno je isključiti druga osnovna stanja prije postavljanja dijagnoze primary erythema nodosum. Može ukazivati na pojavu sistemskih bolesti kao što su infekcije, upale, rak ili reakcije na lijekove. Uobičajeni okidači uključuju strep infections, tuberculosis, sarcoidosis, Behçet's disease, inflammatory bowel disease, certain medications, and pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis se odnosi na niz različitih upalnih stanja koja utiču na masno tkivo ispod kože. Ova stanja su neuobičajena kod djece. Panniculitis može biti ili glavni problem u sistemskom stanju ili reakcija sekundarna na faktore poput infekcije, ozljede ili određenih lijekova. Bez obzira na uzrok, većina tipova panniculitis pokazuje slične simptome, uključujući bolne, crvene čvorove ispod kože.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , upala masnog sloja ispod kože, rijetko je stanje koje se obično manifestira kao natečeni čvorići ili mrlje. Erythema nodosum (EN) je najčešći tip, često izazvan raznim faktorima. Dok oko 55% slučajeva nema jasan uzrok, uobičajeni okidači uključuju infekcije, lijekove, određene bolesti kao što su sarkoidoza i upalna bolest crijeva, trudnoća i rak. EN se obično javlja kod tinejdžera i mladih odraslih osoba, češće kod žena. Često mu prethodi opći osjećaj bolesti koji traje jednu do tri sedmice, sa simptomima kao što su groznica i problemi s gornjim disajnim putevima. Zatim se pojavljuju crveni čvorići, obično na vanjskim stranama ruku i nogu, uzrokujući bol. Tačan uzrok EN nije u potpunosti shvaćen, ali se vjeruje da uključuje imune komplekse u malim krvnim žilama masnog sloja, što dovodi do upale. Tipično, biopsija pokazuje upalu u masnom sloju bez oštećenja krvnih sudova. Čak i bez specifičnog liječenja osnovnog uzroka, EN se često rješava sam. Dakle, većini pacijenata je potrebna samo podrška za svoje simptome.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Erythema nodosum dijagnosticira se klinički. Biopsija se može uzeti i mikroskopski pregledati kako bi se potvrdila neizvjesna dijagnoza. Potrebno je uraditi rendgenski snimak grudnog koša kako bi se isključile plućne bolesti, posebno sarkoidoza i tuberkuloza.