Više informacija ― Bosanski

Pigmented purpuric dermatoses (PPD) su grupa kožnih stanja obilježena malim dijelovima krvarenja ispod kože zbog upale kapilara. PPD obično počinje kao crvene do ljubičaste mrlje koje kasnije postaju zlatno‑smeđe kako se hemosiderin reapsorbira.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.

Schamberg disease je najčešći tip pigmented purpuric dermatoses (PPDs), koji su hronična stanja kože karakterizirana malim crvenim ili ljubičastim mrljama i povećanom obojenosti kože (mrlje smeđe, crvene ili žute). PPD-ovi su klasifikovani u pet tipova: Schamberg's purpura, Majocchi purpura (Majocchi purpura), lichen aureus, Gougerot‑Blum purpura, ekzematoidna purpura Doucasa i Kapetanakisa (eczematoid‑like purpura of Doucas and Kapetanakis). Schamberg disease (SD) je također poznat kao progresivna pigmentarna dermatoza Schamberga (progressive pigmentary dermatosis of Schamberg), purpura pigmentosa progresivna i Schamberg's purpura.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.

Analizirane su informacije o 113 pacijenata sa PPD, uključujući 38 koji su podvrgnuti biopsiji kože za ovu studiju. Najčešći klinički tip bila je Schambergova bolest (Schamberg disease) (60,5%). Ostala stanja uz PPD su hipertenzija (15,8%), dijabetes (10,5%) i drugi. Anamneza uzimanja lijekova otkrila je statine (statins) (13,2%), beta blokatori (beta blockers) (10,5%) i druge. Mogući faktori povezani sa PPD-om su nedavna infekcija gornjih disajnih puteva (upper respiratory infection) (5,3%), produženo stajanje koje dovodi do visokog ortostatskog pritiska (2,6%) i naporno vežbanje (2,6%). Liječenje je primijenjeno na 36 pacijenata (94,7%) – oralni antihistaminici (oral antihistamines), pentoxifylline, topikalni steroidi (topical steroids) i/ili fototerapija (phototherapy).
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.