Riehl melanosis - Riehl Melanoza
https://en.wikipedia.org/wiki/Riehl_melanosis
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References
Riehl Melanosis 32491369 NIH
Riehl melanosis je često poznat kao pigmentirani kontaktni dermatitis. To je tip kožnog stanja uzrokovanog alergijama, obično izazvanim mirisom i drugim supstancama koje se nalaze u kozmetičkim proizvodima. Iako je klasifikovan kao oblik dermatitisa, Riehl melanosis pokazuje promjene pigmentacije na koži, uz samo minimalne znakove iritacije. Češći je kod osoba s tamnijim tonom kože. Nedavna istraživanja su ispitala učinkovitost mid‑fluence Q‑switched 1064‑nm lasera (QSNY) za uklanjanje duboke pigmentacije povezane s Riehl melanosisom. Druga studija kombinovala je različite terapije, uključujući low‑fluence 1064‑nm Q‑switched Nd:YAG laser, kremu s hidrokinonom i oralni tranexamic acid, što je dovelo do značajnog poboljšanja kod većine pacijenata.
Riehl melanosis (RM), commonly called pigmented contact dermatitis, is considered an acquired form of allergic contact dermatitis, typically to fragrance and other ingredients of cosmetic products. Although it is considered as a dermatitis, it presents clinically with hyperpigmentation over the face and shows pigment incontinence with minimal eczematous changes on histology. The condition is more commonly seen in dark-skinned people, causing an important psychosocial impact. A recent study showing the higher effectiveness of mid-fluence QSNY 1064-nm laser in targetting the deep pigmentation of RM has also been conducted. Another study used a combination of therapies to include low-fluence, 1064-nm, Q-switched Nd: YAG laser, hydroquinone cream, and oral tranexamic acid, with the majority of patients experiencing significant improvement.
Research Advances in the Treatment of Riehl’s Melanosis 37168093 NIH
Riehl's melanosis je vrsta kožnog stanja uzrokovanog kontaktom s određenim alergenima i izlaganjem sunčevoj svjetlosti. Uzrokuje brzu, progresivnu sivo‑smeđu pigmentaciju kože, što može značajno utjecati na pacijenta i psihički i fizički. Iako je tačan uzrok Riehl's melanosis još uvijek nepoznat, postojeća istraživanja ukazuju na snažnu vezu s izloženošću alergenima. Za tretman su isprobani i tradicionalni lijekovi i laserska terapija, često uz korištenje sredstava za izbjeljivanje kože. Laserska terapija, posebno korištenjem Q‑switched Nd:YAG lasera, pokazala je obećavajuće rezultate u liječenju Riehl's melanosis. Kombinacija različitih pristupa liječenju dovela je do pozitivnih rezultata.
Riehl's melanosis (RM) is a contact photodermatitis, with fast progressive gray-brown skin pigmentation as the main manifestation, which can seriously affect the psychology and physiology of patients. Currently, although the etiological factors of Riehl's melanosis is still be unknown, the existing literature proves clearly the cause of it is related to the contacting with suspected allergens. For decades, there has been no standard method for the treatment of RM, but with both conventional drug therapy and laser therapy having been attempted. Topical application of bleaching agents is mainly used as an auxiliary treatment modality. The laser treatment modality remains a hot spot, among which Q-switched Nd:YAG laser is well received for RM. Positive outcomes have been achieved by the combined treatment modalities attempted in recent years also achieve positive outcomes.