Acne
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Acne in a zona di u torsu. A parti suprana di u torsu è u spinu sò spazii cumuni di l'acne.
References
L'acne, a cundizione di a pelle più cumuna in i Stati Uniti, hè un problema persistente di a pelle inflamatoria. U trattamentu hà per scopu di indirizzà quattru fatturi principali chì cuntribuiscenu à l'acne: a pruduzzione eccessiva di sebum, l'accumulazione di cellule di a pelle, a colonizazione di Propionibacterium acnes, è a inflammazione risultante. I retinoidi topici gestiscenu efficacemente e lesioni infiammatorie è non-inflamatorii prevenendu è riducendu i comedoni mentre indirizzanu l'infiammazione. U perossu di benzoile, dispunibule in vendita, hè un agentu bactericida senza prumove a resistenza bacteriana. Mentre chì l'antibiotici topichi è orali travaglianu solu, cumminendu cù retinoidi topichi aumenta a so efficacità. L'aggiunta di perossu di benzoile à a terapia antibiotica riduce u risicu di resistenza bacteriana. L'isotretinoina orale, appruvata per l'acne severa è stubborn, hè amministrata à traversu u prugramma iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
I trattamenti tematichi cumuni per l'acne includenu benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. L'antibiotici orali sò longu statu una parte chjave di u trattamentu di l'acne, in particulare per i casi moderati à severi. Funcionanu megliu quandu s'utilice cù un retinoide topicu è BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin tutti anu dimustratu evidenza di efficacità.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
I retinoidi topichi sò sempre cunsigliati per trattà l'acne. Quandu s'utilice l'antibiotici sistemichi o topichi, hè impurtante cumminà cù perossu di benzoyl è retinoids, ma solu per 12 settimane. Isotretinoin hè riservatu à i casi severi d'acne chì ùn anu micca rispostu à altri trattamenti. Mentri ci hè una certa evidenza per i trattamenti fisichi cum'è a terapia laser è i peelings chimichi, è ancu approcci cumplementarii cum'è u velenu d'api purificatu è certi dieti, a so efficacità hè sempre incerta.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Diversi studii anu vistu cumu l'alimenti diffirenti affettanu l'acne in i pazienti. Anu trovu chì e persone cun acne chì manghjanu l'alimenti cù una carica glicemica bassa tendenu à avè menu spots d'acne cumparatu cù quelli chì manghjanu l'alimenti cù una carica glicemica alta. Dairy hè statu ancu studiatu in relazione à l'acne. Sembra chì certe proteine in u latti puderanu cuntribuisce più à l'acne cà u cuntenutu di grassu o di latti generale. L'altri ricerche anu focu annantu à l'acidi grassi omega-3 è l'acidu γ-linoleic. Suggerisce chì e persone cun acne puderanu prufittà di manghjà più pesci è olii sani per aumentà a so ingesta di questi acidi grassi. Studi recenti nantu à i probiotici per l'acne mostranu risultati promettenti, ma più ricerca hè necessaria per cunfirmà questi primi risultati.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
In i dui sessi, l'hormone chjamati androgeni parevanu esse parti di u mecanismu sottumessu, pruvucannu a produzzione aumentata di sebum. Un altru fattore cumuni hè a crescita eccessiva di u bacteriu Cutibacterium acnes, chì hè presente nantu à a pelle.
I trattamenti appiicati direttamente à a pelle affettata, cum'è l'acidu azelaic, u perossu di benzoile è l'acidu salicylic, sò cumunimenti usati. L'antibiotici è i retinoidi sò dispunibuli in formulazioni chì sò appiicati à a pelle è pigliati per bocca per u trattamentu di l'acne. In ogni casu, a resistenza à l'antibiotici pò esse sviluppatu com'è u risultatu di a terapia antibiotica. Diversi tipi di pilule di cuntrollu di nuvità pò aiutà à prevene l'acne in e donne. U trattamentu precoce è aggressivu di l'acne cù l'isotretinoina pò esse utile per diminuisce a cumplicazione à longu andà in l'individui.
○ Trattamentu
Adapalene gel pò esse usata largamente perchè suppresses a secrezione di sebum è hà l'effettu di suppressing the recurrence of acne. U gel di Adapalene pò irritate a pelle se troppu hè appiicatu inizialmente. U perossu di Benzoyl è l'acidu azelaic, invece, ponu esse usatu nantu à i siti di l'acne inflamatorii perchè aiutanu à a inflamazioni. In generale, u trattamentu longu di 1 mesi o più hè necessariu per vede un effettu.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction