Angiofibroma
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References
Cutaneous angiofibromas pò appare in diverse parti di u corpu. Nantu à a faccia, sò spessu cunnisciuti cum'è papule fibru o adenoma sebaceum; nantu à u pene, sò chjamati pearly penile papules ; sottu à u chiovu, sò chjamati angiofibromas periungual o tumuri di Koenen; è in bocca, sò chjamati fibromi orali. L'angiofibromi faciali sò una caratteristica prominente di tuberous sclerosis (TS) , un disordine ereditatu chì afecta a pelle, i rini, u core, u cervellu è i pulmoni. Di solitu si sviluppanu nantu à a faccia durante a zitiddina o a prima età adulta in individui cù TS. Avè trè o più angiofibromi faciali o dui o più angiofibromi periungual hè cunsideratu significativu in u diagnosticu di TS. Inoltre, parechji angiofibromi faciali ponu esse prisenti in cundizioni (multiple endocrine neoplasia type 1 (MEN-1) è Birt-Hogg-Dubé syndrome) . Pearly penile papules si trovanu longu u margine coronale è u sulcus di u pene. Sò bumps persistenti, indolori più cumuni in l'omi incircuncisi.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
1) faccia
Fibrous papule
2) pene
Pearly penile papule
3) sottu à una unghia o unghia
Periungual angiofibroma