Staphylococcal scalded skin syndrome - Sindrome Di A Pelle Scalata Stafilococca
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Un zitellu cù Sindrome Di A Pelle Scalata Stafilococca (Staphylococcal scalded skin syndrome)
References
Staphylococcal Scalded Skin Syndrome hè una cundizione induve a pelle perde per via di tossine prodotte da certi tipi di bacteria Staphylococcus. Hè pocu cumuni in i zitelli più di sei anni. Pò esse ancu in adulti cù sistemi immune debilitatu o prublemi renali seri. A caratteristica principale hè un peeling estensivu di a pelle dopu a inflamazioni. A gravità varieghja da uni pochi di vesciche à a perdita di a pelle diffusa, chì pò causà severi gocce in a temperatura di u corpu è inestabilità in a pressione di sangue.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
Un zitellu di 10 mesi hè ghjuntu cù u nasu chì cola è ùn manghja micca bè. I medichi anu dettu chì era una infezione respiratoria superiore. Dui ghjorni dopu, hà vultatu perchè ùn era micca megliu è hà avutu novi prublemi cum'è a faccia gonfia è a pelle irritata intornu à a bocca. In i dui ghjorni dopu, u zitellu hà peghju. E so braccia è i so gammi s'inflavanu è a so pelle cuminciò à sguassate. Torna à l'uspidale, i medichi anu nutatu un rash rossu nantu à a so faccia è in i plegamenti di a so pelle, chì sbiancava quandu si toccu. L'anu diagnosticatu cù staphylococcal scalded skin syndrome (SSSS) è l'anu principiatu cù antibiotici per via di una vena.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
Una zitella di 2 anni si prisenta cun un rash in tuttu u corpu chì s'era sviluppatu annantu à l'ora di 48, dopu à morse d'insetti nantu à a so faccia u ghjornu prima. Duranti l'esaminazione, hà avutu una rash diffusa fatta di picculi bumps chì si fusionavanu, è quandu ligeramente strofinatu, a so pelle mostrava segni di signu Nikolsky. Ùn ci era micca segni di l'eruzione chì affettava e so mucosa. I testi nantu à u so sangue ùn anu micca mostratu segni d'infezione.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
U sindromu hè indottu da l'exotoxins epidermolytic (exfoliatin) A è B, chì sò liberati da S. aureus. U prognosi di sindrome di a pelle scalata stafilococca (staphylococcal scalded skin syndrome) in i zitelli hè eccellente, cù risuluzione cumpleta in 10 ghjorni di trattamentu, è senza cicatrisu significativu. In ogni casu, u sindrome di a pelle scalata stafilococca (staphylococcal scalded skin syndrome) deve esse differenziatu cù cura da a necrolisi epidermica tossica, chì porta un pronostico poveru.
○ Diagnosi è Trattamentu
Misdiagnosis cum'è lesioni di eczema, cum'è dermatite atopica, è l'applicazione di unguentu steroidu aggrava e lesioni. Per piacè cercate l'assistenza medica u più prestu pussibule mentre applicate unguentu antibioticu.
#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)