Dermatofibroma - Dermatofibrom
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Typický případ Dermatofibrom (Dermatofibroma) ― Tvrdý uzlík na končetině. Dermatofibrom (Dermatofibroma) je poměrně častý benigní nádor.
References
Dermatofibroma je běžné kožní onemocnění vyskytující se většinou na pažích nebo nohou. Projevuje se jako pevné hrudky pod kůží, často o velikosti menší než 1 centimetr. I když je to obvykle bezbolestné, může být spojeno s drobnými zraněními, jako jsou kousnutí hmyzem nebo bodnutí trnem. Dermatofibromy mohou postihnout kohokoli, ale jsou častější u žen ve věku 20 až 40 let. Obvykle jsou benigní, ale někdy se mohou po odstranění vrátit. Je důležité odlišit dermatofibromy od agresivnějšího kožního nádoru zvaného dermatofibrosarcoma protuberans.
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
Preferovanou léčbou lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, and epidermoid cysts je chirurgické odstranění. Cherry angiomas and sebaceous hyperplasia se běžně léčí laserovou terapií nebo elektrodesikací. Kryoterapie a excize holení jsou oblíbenou volbou pro acrochordons and seborrheic keratoses. Pokud si rodinný lékař není jistý diagnostikou nebo léčbou léze nebo pokud biopsie potvrdí melanom, doporučuje se doporučení ke specialistovi.
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, epidermoid cysts is surgical removal. Cherry angiomas, sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons, seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, epidermoid cysts is surgical removal. Cherry angiomas, sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons, seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.
Dermatofibromy se mohou vytvořit jako reakce na předchozí zranění, jako je bodnutí hmyzem nebo bodnutí trnem. Dermatofibromy jsou klasifikovány jako benigní kožní léze, což znamená, že jsou zcela neškodné, ačkoli dermatofibromy mohou být zaměňovány s různými podkožními nádory. Hluboce penetrující dermatofibromy může být obtížné odlišit, dokonce i histologicky, od vzácných maligních fibrohistocytárních nádorů, jako je „dermatofibrosarcoma protuberans“.
○ Diagnostika a léčba
Většina je benigních, ale velké léze (>5 mm) mohou vyžadovat biopsii.
#Dermoscopy
#Skin biopsy