Lymphangioma - Lymffangioma
Lymphangioma (Lymphangioma) yn camffurfiadau yn y system lymffatig a nodweddir gan cystau tenau‑waliau. Gall y camffurfiadau hyn ddigwydd ar unrhyw oedran a gallant gynnwys unrhyw ran o'r corff, ond mae 90 % yn digwydd mewn plant llai na 2 flwyddyn oed ac yn cynnwys y pen a'r gwddf. Yn gyffredin caiff lymphangiomas eu diagnosio cyn geni gan ddefnyddio uwchsonograffeg fetws. Gall lymphangiomas a gafodd eu caffael eu datblygu o drwm, llid, neu rwystr lymffatig. Gan nad oes ganddynt unrhyw siawns o ddod yn falaen, mae lymphangiomas fel arfer yn cael eu trin am resymau cosmetig yn unig.
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ReferencesMae Lymphangioma hefyd yn cael ei adnabod fel malffurfiad lymffatig (LM). Mae’n anhwylder fasgwlaidd sy’n bresennol o enedigaeth. Fe’i nodweddir gan dwf annormal mewn cyffuryn lymffatig cyn ac ar ôl genedigaeth. Mae Lymphangioma yn effeithio ar tua 1 o bob 2000 i 4000 o bobl, heb unrhyw wahaniaeth arwyddocaol rhwng rhyw neu hil. Mae’r rhan fwyaf o achosion (80‑90 %) yn cael eu diagnosio cyn dwy oed. Mae symptomau’n amrywio’n fawr, o chwyddo lleol i annormaleddau helaeth yn y sianeli lymffatig, weithiau’n arwain at elfantiasis. Er enghraifft, gall lymphangioma yn y gwddf a’r wyneb achosi elfantiasis, ac mewn achosion difrifol, anffurfiad. Pan fydd yn effeithio ar y tafod, gall arwain at ordyfiad gyn a dannedd wedi’u cam‑alinio. Yn y pen a’r gwddf, gall achosi problemau anadlu ac argyfyngau sy’n bygwth bywyd. Yn y llygaid, gall achosi colli golwg, symudiad llygaid cyfyngedig, amrannau sy’n chwyddo, a exophthalmos (exophthalmos). Gall cynnwys aelodau’r corff achosi chwyddo a thwf annormal cyffurynau ac asgyrn. Mae’r tiwmor hwn fel arfer yn tyfu’n araf, ond gall heintiau, newidiadau hormonaidd, neu anaf achosi twf cyflym, gan achosi risgiau sy’n bygwth bywyd y mae angen triniaeth frys arnynt.
Lymphangioma (lymphatic malformation, LM), a congenital vascular disease, is a low-flow vascular abnormality in lymphatic diseases that is characterized by excessive growth of lymphatic tissue during prenatal and postpartum development. The incidence rate of LM is ~1:2000–4000, with no variation between genders and races. Most patients (80–90%) are diagnosed before the age of two. The clinical manifestations of lymphangioma are quite different among patients, varying from local swelling leading to superficial mass to a large area of diffuse infiltrating lymphatic channel abnormalities resulting in elephantiasis. Cervicofacial LM can cause facial elephantiasis, and in some severe cases, it can lead to serious disfigurement of the face. Tongue LM can lead to mandibular overgrowth and occlusal asymmetry, and oral and cervical LM can cause obstructive acute respiratory distress and life-threatening situations. Orbital LM may lead to decreased vision, decreased extraocular muscle movement, ptosis and exophthalmos. LM of the extremities can trigger swelling or gigantism, accompanied by overgrowth of soft tissue and bones. LM usually grows slowly and steadily, but under certain conditions, such as infection, hormonal changes or trauma, it can grow explosively and become a life-threatening disease requiring immediate treatment.
Lymphangioma (lymphatic malformation, LM), a congenital vascular disease, is a low-flow vascular abnormality in lymphatic diseases that is characterized by excessive growth of lymphatic tissue during prenatal and postpartum development. The incidence rate of LM is ~1:2000–4000, with no variation between genders and races. Most patients (80–90%) are diagnosed before the age of two. The clinical manifestations of lymphangioma are quite different among patients, varying from local swelling leading to superficial mass to a large area of diffuse infiltrating lymphatic channel abnormalities resulting in elephantiasis. Cervicofacial LM can cause facial elephantiasis, and in some severe cases, it can lead to serious disfigurement of the face. Tongue LM can lead to mandibular overgrowth and occlusal asymmetry, and oral and cervical LM can cause obstructive acute respiratory distress and life-threatening situations. Orbital LM may lead to decreased vision, decreased extraocular muscle movement, ptosis and exophthalmos. LM of the extremities can trigger swelling or gigantism, accompanied by overgrowth of soft tissue and bones. LM usually grows slowly and steadily, but under certain conditions, such as infection, hormonal changes or trauma, it can grow explosively and become a life-threatening disease requiring immediate treatment.
Yn yr astudiaeth ôl-weithredol hon, fe wnaethom adolygu 24 o blant a gafodd lymphangioma a chael eu trin â phigiadau o hydoddiant bleomycin rhwng Ionawr 1999 a Rhagfyr 2004. Aeth y rhan fwyaf o'r briwiau (63 %) i ffwrdd yn llwyr, cafodd 21 % ymateb da, ac 16 % ymateb gwael. Daeth y tiwmor yn ôl mewn 2 claf. A chafodd dau arall ffurfiad absessau yn y safle mewnbwn. Ni welwyd unrhyw gymhlethdodau difrifol neu effeithiau gwaedol eraill.
This is a retrospective study of 24 children diagnosed with lymphangioma and treated with intralesional injection of bleomycin aqueous solution from January 1999 to December 2004. Complete resolution was seen in 63% (15/24) of lesions, 21% (5/24) had good response and 16% (4/24) had poor response. The tumour recurred in 2 patients. Two other patients had abscess formation at the site of injection. No other serious complications or side effects were observed.
This is a retrospective study of 24 children diagnosed with lymphangioma and treated with intralesional injection of bleomycin aqueous solution from January 1999 to December 2004. Complete resolution was seen in 63% (15/24) of lesions, 21% (5/24) had good response and 16% (4/24) had poor response. The tumour recurred in 2 patients. Two other patients had abscess formation at the site of injection. No other serious complications or side effects were observed.
Mae'r prif fathau o lymphangioma fel a ganlyn - lymphangioma circumscriptum, cavernous lymphangioma, cystic hygroma, lymphangioendothelioma. Mae'r rhain yn cyfrif am tua 26 % o diwmorau fasgwlaidd anfalaen mewn plant ond maent yn llai cyffredin mewn oedolion. Mae lymphangioma circumscriptum, y math mwyaf cyffredin, yn dangos dwythellau lymffatig yn ymestyn drwy'r epidermis, gan ffurfio fesiglau clir llawn hylif sy'n debyg i grifft llyffant, ynghyd â chwyddedyn cyhyrol cysylltiedig. Mae'n arferol ei weld ar y coesau agos, y corff, a'r arlwy, lle mae rhwydwaith lymffatig cyfoethog. Daeth menyw 71 oed i'n clinig gyda chwyddedyn parhaus yn ei ddwy goes, papules labial pinc, pruritis, a hylif lymff yn llifo. Fe wnaethom dynnu'r papules trwy wneud labiectomi mawr dwbl i lefel ffasia Colles, gan gadw'r clitoris a'r pedchedd.
The predominant types of lymphangioma are lymphangioma circumscriptum (LC), cavernous lymphangioma, cystic hygroma, and lymphangioendothelioma. These entities account for approximately 26% of benign vascular tumors in children but are rarer in adults. LC is the most common form of cutaneous lymphangioma and is characterized by superficial lymphatic ducts protruding through the epidermis. This condition results in clusters of clear fluid-filled vesicles resembling frog spawn and associated tissue edema. It is usually found on the proximal extremity, trunk, and axilla, which has an abundant lymphatic system. A 71-year-old female presented to our outpatient clinic with persistent edema of both lower limbs, clusters of pink labial papules, pruritus, and watery lymph oozing. We removed all the papules by performing bilateral major labiectomy down to the level of Colles' fascia, sparing the clitoris and fourchette.
The predominant types of lymphangioma are lymphangioma circumscriptum (LC), cavernous lymphangioma, cystic hygroma, and lymphangioendothelioma. These entities account for approximately 26% of benign vascular tumors in children but are rarer in adults. LC is the most common form of cutaneous lymphangioma and is characterized by superficial lymphatic ducts protruding through the epidermis. This condition results in clusters of clear fluid-filled vesicles resembling frog spawn and associated tissue edema. It is usually found on the proximal extremity, trunk, and axilla, which has an abundant lymphatic system. A 71-year-old female presented to our outpatient clinic with persistent edema of both lower limbs, clusters of pink labial papules, pruritus, and watery lymph oozing. We removed all the papules by performing bilateral major labiectomy down to the level of Colles' fascia, sparing the clitoris and fourchette.
