Onychomysosis
☆ Yng nghanlyniadau Stiftung Warentest 2022 o’r Almaen, roedd boddhad defnyddwyr â ModelDerm ond ychydig yn is nag ymgynghoriadau telefeddygaeth taledig.
Ewinedd y traed a effeithiwyd gan Onychomysosis
Traed person â haint ffwngaidd ewinedd ddeg wythnos i mewn i gwrs o feddyginiaeth terbinafine geneuol. Sylwch ar y band o dyfiant ewinedd iach y tu ôl i'r ewinedd heintiedig sy'n weddill.
References
Antifungals systemig yw'r driniaeth fwyaf effeithiol. Mae meta-ddadansoddiadau yn dangos cyfraddau iachâd mycotig fel a ganlyn: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48% . Mae dadbridiad ewinedd cydredol yn cynyddu cyfraddau gwella ymhellach. Mae therapi amserol gyda ciclopirox yn llai effeithiol; mae ganddo gyfradd fethiant o fwy na 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Mae onychomycosis yn haint ffwngaidd sy'n effeithio ar yr ewinedd. Pan gaiff ei achosi gan ddermatoffytau, fe'i gelwir yn tinea unguium. Mae onychomycosis yn cynnwys heintiau a achosir gan ddermatoffytau, burumau a llwydni. Gelwir problem ewinedd nad yw'n cael ei hachosi gan haint ffwngaidd yn nail dystrophy. Er y gall effeithio ar ewinedd ac ewinedd, mae onychomycosis ewinedd traed yn fwy cyffredin. Mae'r erthygl hon yn trafod gwahanol agweddau ar onychomycosis ewinedd traed, megis ei effaith, mathau clinigol, cyfnodau, diagnosis, a thriniaeth. Er nad yw'n fygythiad bywyd, gall onychomycosis arwain at gymhlethdodau difrifol fel llid yr isgroen, sepsis, haint esgyrn, niwed i feinwe, a cholli ewinedd.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Mae Terbinafine yn feddyginiaeth sy'n ymladd heintiau ffwngaidd trwy rwystro squalene epoxidase. Mae'n effeithiol yn erbyn sawl math o ffyngau croen ac fe'i cymeradwyir ar gyfer trin ffwng ewinedd pan gaiff ei gymryd ar lafar. Er bod y rhan fwyaf o sgîl-effeithiau fel cur pen a phroblemau stumog yn fach ac yn diflannu ar eu pen eu hunain, gall newidiadau mewn blas (dysgeusia) amrywio o ysgafn i ddifrifol, gan arwain weithiau at golli pwysau. Mae newidiadau blas parhaol yn brin ond wedi cael eu hadrodd.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Mae onychomycosis yn haint ffwngaidd sy'n effeithio ar ewinedd. Mae tua 90% o heintiau ewinedd traed a 75% o heintiau ewinedd bysedd yn cael eu hachosi gan ffyngau (Trichophyton mentagrophytes, Trichophyton rubrum) . Ymhlith y symptomau mae afliwiad ewinedd, tewychu, gwahanu oddi wrth y gwely ewinedd, a gordyfiant. Mae triniaeth fel arfer yn cynnwys meddyginiaethau llafar fel terbinafine neu itraconazole, gyda thriniaethau amserol yn opsiwn ar gyfer achosion ysgafn i gymedrol.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Ymddengys mai'r feddyginiaeth gwrthffyngaidd terbinafine a gymerir trwy'r geg yw'r mwyaf effeithiol ond mae terbinafine yn gysylltiedig â sgîl-effaith yr afu.
Mae onychomysosis yn digwydd mewn tua 10 y cant o'r boblogaeth oedolion, gyda phobl hŷn yn cael eu heffeithio'n amlach. Mae gwrywod yn cael eu heffeithio yn amlach na merched. Mae onychomysosis yn cynrychioli tua hanner y clefyd ewinedd. Mae hyn yn golygu y gall anffurfiad ewinedd traed hefyd ddod o achosion heblaw onychomycosis.
○ Triniaeth - Cyffuriau OTC
Mae'n anodd trin onychomycosis gyda meddyginiaethau amserol oherwydd ei bod yn anodd i gyffuriau dreiddio i ewinedd traed trwchus.
#Ketoconazole
#Clotrimazole
#Miconazole
#Terbinafine
#Butenafine [Lotrimin]
#Tolnaftate
○ triniaeth
Fel arfer mae angen triniaeth hirdymor nes bod ewinedd traed heintiedig wedi'u tynnu allan yn llwyr.
#Terbinafine (oral)
#Itraconazole
#Efinaconazole lacquer [Jublia]
#Ciclopirox lacquer