Panniculitis
☆ Yng nghanlyniadau Stiftung Warentest 2022 o’r Almaen, roedd boddhad defnyddwyr â ModelDerm ond ychydig yn is nag ymgynghoriadau telefeddygaeth taledig.
Twbercwlosis yw un o'r achosion arwyddocaol.
References
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis ffurfio grŵp heterogenaidd o glefydau llidiol sy'n cynnwys y meinwe adipose isgroenol. Mae'r anhwylderau hyn yn brin mewn plant. Gall y panniculitis fod yn brif broses mewn anhwylder systemig neu'n broses eilaidd sy'n deillio o haint, trawma neu amlygiad i feddyginiaeth. Mae gan y rhan fwyaf o fathau o panniculitis yr un cyflwyniad clinigol (waeth beth fo'r achoseg) , gyda nodiwlau isgroenol tendr, erythematous.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , llid y braster isgroenol, fel arfer yn cyflwyno gyda nodules llidiol. Erythema nodosum (EN) yn glinigol yw'r math mwyaf cyffredin o pannicwlitis. Er bod hyd at 55% o EN yn cael ei ystyried yn idiopathig, mae'r achosion mwyaf cyffredin yn cynnwys heintiau, cyffuriau, salwch systemig fel sarcoidosis a chlefyd y coluddyn llid, beichiogrwydd, a malaenedd. Mae EN fel arfer yn bresennol yn yr arddegau a'r 20au, ac fe'i gwelir yn fwy cyffredin ymhlith merched. Yn aml caiff ei ragflaenu gan brodrom amhenodol o wythnos i dair wythnos, a all gynnwys twymyn, anhwylder, a symptomau haint y llwybr anadlol uchaf. Yna mae briwiau croenol yn dilyn, wedi'u lleoli'n nodweddiadol ar agwedd allanol yr aelodau. Mae'r briwiau'n boenus, crwn neu hirgrwn, nodau coch heb fod yn wlserol wedi'u codi ychydig. Ni ddeellir union bathogenesis EN, er y credir ei fod yn deillio o ddyddodiad cyfadeiladau imiwn yn gwythiennau'r septae mewn braster isgroenol, gan achosi panniculitis niwtroffilig. Hyd yn oed heb therapi penodol ar gyfer cyflwr achosol, mae EN yn datrys heb driniaeth yn y rhan fwyaf o achosion.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
Mae "Erythema nodosum" yn fath o panniculitis a nodweddir gan nodiwlau coch tyner, 1-10 cm, sy'n gysylltiedig â symptomau systemig gan gynnwys twymyn, malais, a phoen yn y cymalau. Gall nodiwlau gilio dros gyfnod o 2-6 wythnos heb wlserau na chreithiau. Mae erythema nodosum yn gysylltiedig â heintiau, gan gynnwys Hepatitis C, EBV a thwbercwlosis, beichiogrwydd, lymffoma nad yw'n Hodgkin, a chanser y pancreas.