Mwy o wybodaeth ― Cymraeg

Mae Pigmented purpuric dermatoses (PPD) yn grŵp o gyflyrau croen a nodir gan ardaloedd bach o waedu o dan y croen oherwydd llid capilari. Mae PPD fel arfer yn dechrau fel smotiau coch i borffor sy'n troi'n frown euraidd yn ddiweddarach wrth i'r hemosiderin gael ei adamsugno.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.

Schamberg disease yw'r math mwyaf cyffredin o pigmented purpuric dermatoses (PPDs) , sef cyflyrau croen cronig a nodweddir gan smotiau bach coch neu borffor, a mwy o liw croen (darnau brown, coch neu felyn) . Mae PPDs yn cael eu dosbarthu i bum math: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, eczematoid-like purpura of Doucas and Kapetanakis. Mae Schamberg disease (SD) hefyd yn cael ei adnabod fel progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressiva, Schamberg's purpura. Mae'n effeithio'n bennaf ar wrywod ac yn nodweddiadol mae'n ymddangos ar y coesau isaf, ond gall hefyd ddigwydd ar y cluniau, y pen-ôl, y boncyff, neu'r breichiau.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.

Dadansoddwyd gwybodaeth am 113 o gleifion â PPD, gan gynnwys 38 a gafodd biopsi croen ar gyfer yr astudiaeth hon. Y math clinigol mwyaf cyffredin oedd clefyd Schamberg (60. 5%) . Cyflyrau eraill ochr yn ochr â PPD oedd gorbwysedd (15. 8%) , diabetes (10. 5%) , ac eraill. Datgelodd hanes meddyginiaeth statins (13. 2%) , atalyddion beta (10. 5%) , ac eraill. Roedd ffactorau posibl yn gysylltiedig â PPD yn cynnwys haint anadlol uwch diweddar (5. 3%) , sefyll am gyfnod hir yn arwain at bwysau orthostatig uchel (2. 6%) , ac ymarfer corff egnïol (2. 6%) . Rhoddwyd triniaeth i 36 o gleifion (94. 7%) - oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.