Acanthosis nigricans
☆ I 2022 Stiftung Warentest-resultaterne fra Tyskland var forbrugernes tilfredshed med ModelDerm kun lidt lavere end med betalte telemedicinske konsultationer.
Det er almindeligt hos overvægtige mennesker.
References
Acanthosis nigricans er en kutan manifestation af en underliggende tilstand. Det vises ofte i hudfolder som hals, armhuler og lyske, og ligner fløjlsbløde mørke pletter med uklare kanter. Denne tilstand er normalt forbundet med diabetes og insulinresistens, men i sjældne tilfælde kan den pege på kræft i kroppen. Det kan også dukke op på grund af hormonproblemer eller ved at tage specifik medicin såsom steroider og p-piller.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans (AN) er en almindelig hudlidelse forbundet med forskellige sundhedsproblemer som insulinresistens, diabetes, fedme, visse kræftformer, hormonelle problemer og reaktioner på medicin. Behandling af AN fokuserer på at adressere de underliggende sundhedsproblemer. I første omgang tjekker læger for tegn på insulinresistenssyndrom, som omfatter fedme, højt kolesteroltal, forhøjet blodtryk og type 2-diabetes. Læger ordinerer ofte topical retinoids som det første behandlingsvalg, hvilket kan hjælpe med fortykkelse af huden. De kan dog muligvis ikke helt behandle mørkfarvning af huden. Andre behandlingsmuligheder som salicylic acid, podophyllin, urea, and calcipotriol kræver også hyppig påføring.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
○ årsager
Det forekommer typisk hos personer yngre end 40 år, kan være genetisk nedarvet og er forbundet med fedme eller endokrinopatier, såsom hypothyroidisme, akromegali, polycystisk ovariesygdom, insulin-resistent diabetes eller Cushings sygdom.
○ Behandling ― OTC-lægemidler
#40% urea cream