Acne - Akne
☆ I 2022 Stiftung Warentest-resultaterne fra Tyskland var forbrugernes tilfredshed med ModelDerm kun lidt lavere end med betalte telemedicinske konsultationer.
Acne i torsoområdet. Den øverste del af torso og ryg er almindelige områder med acne.
References
Acne, den mest almindelige hudlidelse i USA, er et vedvarende inflammatorisk hudproblem. Behandlingen sigter mod at behandle fire hovedfaktorer, der bidrager til acne: overdreven talgproduktion, hudcelleopbygning, Propionibacterium acnes kolonisering og deraf følgende betændelse. Aktuelle retinoider håndterer effektivt både inflammatoriske og ikke-inflammatoriske læsioner ved at forebygge og reducere komedoner, mens de behandler inflammation. Benzoylperoxid, som fås i håndkøb, er et bakteriedræbende middel uden at fremme bakteriel resistens. Mens topiske og orale antibiotika virker alene, øger kombinationen af dem med topiske retinoider deres effektivitet. Tilføjelse af benzoylperoxid til antibiotikabehandling sænker risikoen for bakteriel resistens. Oral isotretinoin, godkendt til svær og genstridig acne, administreres gennem iPLEDGE-programmet.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Almindelige topiske behandlinger for acne omfatter benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, and sulfone agents. Orale antibiotika har længe været en vigtig del af acnebehandling, især for moderate til svære tilfælde. De fungerer bedst, når de bruges sammen med en topisk retinoid og BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, and cephalexin har alle vist bevis for effektivitet.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Aktuelle retinoider anbefales altid til behandling af acne. Når du bruger systemiske eller topiske antibiotika, er det vigtigt at kombinere dem med benzoylperoxid og retinoider, men kun i op til 12 uger. Isotretinoin er forbeholdt alvorlige tilfælde af acne, der ikke har reageret på andre behandlinger. Selvom der er nogle beviser for fysiske behandlinger som laserterapi og kemisk peeling, såvel som komplementære tilgange såsom renset bigift og visse diæter, er deres effektivitet stadig usikker.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Flere undersøgelser har set på, hvordan forskellige fødevarer påvirker acne hos patienter. De fandt ud af, at personer med akne, der spiser fødevarer med en lav glykæmisk belastning, har en tendens til at have færre aknepletter sammenlignet med dem, der spiser fødevarer med en høj glykæmisk belastning. Mejeri er også blevet undersøgt i forhold til acne. Det ser ud til, at visse proteiner i mælk kan bidrage mere til acne end fedtindholdet eller det samlede indhold af mejeriprodukter. Anden forskning har fokuseret på omega-3 fedtsyrer og γ-linolsyre. Det tyder på, at personer med akne kan have gavn af at spise mere fisk og sunde olier for at øge deres indtag af disse fedtsyrer. Nylige undersøgelser af probiotika mod acne viser lovende resultater, men mere forskning er nødvendig for at bekræfte disse tidlige fund.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Hos begge køn ser hormoner kaldet androgener ud til at være en del af den underliggende mekanisme, ved at forårsage øget produktion af talg. En anden fælles faktor er den overdrevne vækst af bakterien Cutibacterium acnes, som er til stede på huden.
Behandlinger påført direkte på den berørte hud, såsom azelainsyre, benzoylperoxid og salicylsyre, er almindeligt anvendte. Antibiotika og retinoider er tilgængelige i formuleringer, der påføres huden og tages gennem munden til behandling af acne. Resistens over for antibiotika kan dog udvikle sig som følge af antibiotikabehandling. Flere typer p-piller kan hjælpe med at forhindre acne hos kvinder. Tidlig og aggressiv behandling af acne ved hjælp af isotretinoin kan være nyttig til at mindske den langsigtede komplikation hos enkeltpersoner.
○ Behandling
Adapalene gel kan bruges bredt, fordi det undertrykker sekretionen af talg og har den effekt, at det undertrykker tilbagefald af acne. Adapalene gel kan irritere huden, hvis der først påføres for meget. Benzoylperoxid og azelainsyre kan derimod bruges på inflammatoriske acnesteder, fordi de hjælper mod betændelse. Generelt kræves der langtidsbehandling på 1 måned eller mere for at se effekt.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction