Acne - Akne
☆ I 2022 Stiftung Warentest-resultaterne fra Tyskland var forbrugernes tilfredshed med ModelDerm kun lidt lavere end med betalte telemedicinske konsultationer.
Acne i torsoområdet. Den øverste del af torsoen og ryggen er almindelige områder, hvor acne kan forekomme.
relevance score : -100.0%
ReferencesAcne, den mest almindelige hudlidelse i USA, er et vedvarende inflammatorisk hudproblem. Behandlingen har til formål at målrette fire hovedfaktorer, der bidrager til acne: overdreven talgproduktion, overproduktion af hudceller, Propionibacterium acnes‑kolonisering og den deraf følgende betændelse. Aktuelle retinoider virker effektivt på både inflammatoriske og ikke‑inflammatoriske læsioner ved at forebygge og reducere komedoner samt behandle betændelse. Benzoylperoxid, som kan købes i håndkøb, er et bakteriedræbende middel, der ikke fremmer bakteriel resistens. Selvom topiske og orale antibiotika kan virke alene, øger kombinationen med topiske retinoider deres effektivitet. Tilføjelse af benzoylperoxid til antibiotikabehandlingen sænker risikoen for bakteriel resistens. Oral isotretinoin, godkendt til svær og genstridig acne, administreres gennem iPLEDGE‑programmet.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Almindelige topiske behandlinger af acne omfatter benzoyl peroxide (BP), salicylic acid, antibiotika, kombinationer af antibiotika med BP, retinoider, kombinationer af retinoider med BP eller antibiotika, azelaic acid og sulfone‑midler. Orale antibiotika har længe været en vigtig del af acnebehandling, især ved moderate til svære tilfælde. De fungerer bedst, når de anvendes sammen med en topisk retinoid og BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin og cephalexin har alle dokumenteret effektivitet.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
De aktuelle retinoider anbefales altid til behandling af acne. Når du anvender systemiske eller topiske antibiotika, bør de kombineres med benzoylperoxid og retinoider, dog højst i 12 uger. Isotretinoin er forbeholdt alvorlige tilfælde af acne, der ikke har reageret på andre behandlinger. Selvom der findes nogle beviser for fysiske behandlinger såsom laserterapi og kemisk peeling, samt komplementære tilgange som renset bigift og visse diæter, er deres effektivitet stadig usikker.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Flere undersøgelser har undersøgt, hvordan forskellige fødevarer påvirker akne hos patienter. De fandt, at personer med akne, som spiser fødevarer med lav glykæmisk belastning, har en tendens til at få færre aknepletter sammenlignet med dem, der spiser fødevarer med høj glykæmisk belastning. Mejeri er også blevet undersøgt i forhold til akne. Det ser ud til, at visse proteiner i mælk kan bidrage mere til akne end fedtindholdet eller det samlede indhold af mejeriprodukter. En anden forskningslinje har fokuseret på omega‑3‑fedtsyrer og γ‑linolsyre. Det tyder på, at personer med akne kan have gavn af at spise mere fisk og sunde olier for at øge deres indtag af disse fedtsyrer. Nylige undersøgelser af probiotika mod akne viser lovende resultater, men der er behov for yderligere forskning for at bekræfte de tidlige fund.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Hos begge køn ser hormoner, kaldet androgener, ud til at være en del af den underliggende mekanisme ved at forårsage øget talgproduktion. En anden fælles faktor er den overdrevne vækst af bakterien Cutibacterium acnes, som naturligt findes på huden.
Behandlinger, der påføres direkte på den berørte hud, såsom azelaic acid, benzoyl peroxide og salicylic acid, er almindeligt anvendte. Antibiotika og retinoider findes både som topiske formuleringer og som oral medicin til behandling af acne. Resistens over for antibiotika kan dog udvikle sig som følge af antibiotikabehandling. Flere typer p‑piller kan hjælpe med at forebygge acne hos kvinder. Tidlig og aggressiv behandling med isotretinoin kan være nyttig til at mindske de langsigtede komplikationer hos enkelte personer.
○ Behandling
Adapalene gel kan anvendes bredt, da den hæmmer talgsekretionen og reducerer tilbagefald af acne. Gel’en kan irritere huden, hvis den påføres i for store mængder. Benzoyl peroxide og azelaic acid kan derimod anvendes på inflammatoriske acneudbrud, da de har antiinflammatorisk effekt. Generelt kræves en behandling på mindst en måned for at se effekt.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction