Amyloidosis - Amyloidose
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I 2022 Stiftung Warentest-resultaterne fra Tyskland var forbrugernes tilfredshed med ModelDerm kun lidt lavere end med betalte telemedicinske konsultationer.
I 2022 Stiftung Warentest-resultaterne fra Tyskland var forbrugernes tilfredshed med ModelDerm kun lidt lavere end med betalte telemedicinske konsultationer.
Klassiske ansigtstræk ved amyloidose (Amyloidosis)
relevance score : -100.0%
ReferencesEn 26‑årig kvinde kom til vores klinik og klagede over et kløende udslæt på benene, som hun havde haft i 10 år. På trods af brug af steroidcremer og tazarotencreme blev udslættet ikke bedre. Hun havde ingen relevant familiehistorie. Da vi undersøgte hende, fandt vi hævede, ru pletter på forsiden af benene, som matchede en sygdom kaldet lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
Lichen Amyloidosis er en sjælden hudlidelse, der er forbundet med vedvarende kløe af ukendt årsag. Det viser sig typisk som klynger af hævede, misfarvede pletter på hudens ydre overflade. Lichen Amyloidosis optræder normalt hos personer i alderen 50‑60 år, og der er desværre ingen kur mod den. De tilgængelige behandlinger virker normalt ikke særlig godt.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen amyloidosis er en kronisk kløende hudtilstand. Den er kendetegnet ved klynger af fortykkede knopper, som hovedsageligt forekommer på ryggen, skinnebenene, lårene og armene. Ved mikroskopisk undersøgelse viser Lichen amyloidosis en ophobning af amyloid i det øverste hudlag samt fortykkelse og udvidelse af det ydre hudlag. Selvom den præcise årsag til Lichen amyloidosis endnu ikke er fuldt forstået, har tidligere undersøgelser knyttet tilstanden til faktorer såsom gnidning eller friktion på huden, celledød, virusinfektioner og andre. Lichen amyloidosis ser ud til at være forbundet med flere andre hudsygdomme, herunder atopic dermatitis, lichen planus og mycosis fungoides.
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
○ Diagnose og behandling
Elektroforese af blod eller urin
Hudbiopsi