Dermatofibroma - Dermatofibrom
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Typisk tilfælde af Dermatofibrom (Dermatofibroma) – en hård knude på lemmet. Dermatofibrom (Dermatofibroma) er en relativt almindelig, godartet tumor.
relevance score : -100.0%
ReferencesDermatofibroma er en almindelig hudlidelse, der oftest forekommer på arme eller ben. Den fremstår som faste knuder under huden, ofte mindre end 1 cm i diameter. Selvom den normalt er smertefri, kan den være forbundet med tidligere mindre skader såsom insektbid eller tornestik. Dermatofibromer kan forekomme hos alle, men er hyppigere hos kvinder i alderen 20–40 år. De er som regel godartede, men kan nogle gange komme tilbage efter fjernelse. Det er vigtigt at skelne dermatofibromer fra den mere aggressive hudtumor dermatofibrosarcoma protuberans.
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
Den foretrukne behandling for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas og epidermoid cysts er kirurgisk fjernelse. Cherry angiomas og sebaceous hyperplasia behandles almindeligvis med laserterapi eller elektrodesikation. Kryoterapi og barbering er populære valg til acrochordons og seborrheic keratoses. Hvis en familielæge er usikker på diagnostisering eller behandling af en læsion, eller hvis en biopsi bekræfter melanom, anbefales henvisning til en specialist.
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, epidermoid cysts is surgical removal. Cherry angiomas, sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons, seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, epidermoid cysts is surgical removal. Cherry angiomas, sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons, seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.
Dermatofibromer kan dannes som en reaktion på tidligere skader, såsom insektbid eller tornestik. Dermatofibromer er klassificeret som godartede hudlæsioner, hvilket betyder, at de er fuldstændig harmløse, selvom de kan forveksles med en række subkutane tumorer. Dybt penetrerende dermatofibromer kan være vanskelige at skelne, selv histologisk, fra sjældne maligne fibrohistocytiske tumorer som dermatofibrosarcoma protuberans.
○ Diagnose og behandling
De fleste er godartede, men store læsioner (>5 mm) kan kræve biopsi.
#Dermoscopy
#Skin biopsy