Lichen planus
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Brede læsioner på begge skinneben er atypiske. I dette tilfælde er andre kroniske allergiske sygdomme (lichen simplex chronicus) normalt mere mistænkte.
Atrophic lichen planus
References
Lichen planus (LP) er en langvarig betændelsestilstand, der for det meste rammer voksne i mellemalderen. Det kan dukke op på huden eller slimhinderne som munden, skeden, spiserøret, stemmeboksen og øjenslimhinden. LP kommer i forskellige former afhængigt af hvordan udslætene ser ud og hvor de optræder. Undersøgelser tyder på, at visse typer LP, som dem der påvirker spiserøret eller øjnene, muligvis ikke er diagnosticeret nok. Nogle former for LP, som de hypertrofiske og erosive typer i munden, kan være særligt belastende og holde i lang tid. Andre faktorer som medicin eller kontakt med visse stoffer kan udløse lignende udslæt.
Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. LP can involve the skin or mucous membranes including the oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. It has different variants based on the morphology of the lesions and the site of involvement. The literature suggests that certain presentations of the disease such as esophageal or ophthalmological involvement are underdiagnosed. The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. LP can significantly affect the quality of life of patients as well. Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP.
Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. LP can involve the skin or mucous membranes including the oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. It has different variants based on the morphology of the lesions and the site of involvement. The literature suggests that certain presentations of the disease such as esophageal or ophthalmological involvement are underdiagnosed. The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. LP can significantly affect the quality of life of patients as well. Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP.
Lichen planus er en hudsygdom, der er præget af lilla, flade knopper og pletter, der kan forårsage intens kløe. Disse hudlæsioner kan være foruroligende, især når de påvirker munden eller kønsorganerne alvorligt. I alvorlige tilfælde kan oral lichen planus endda øge risikoen for at udvikle en type hudkræft. Det kan også påvirke hovedbunden og neglene. Mens årsagen til de fleste tilfælde er ukendt, kan nogle være udløst af visse medikamenter eller hepatitis C-infektion. Behandlingen involverer typisk stærke cremer til lokaliserede tilfælde og orale steroider til mere udbredte.
Lichen planus is a skin condition marked by purplish, flat-topped bumps and patches that can cause intense itching. These skin lesions can be distressing, especially when they affect the mouth or genitals severely. In severe cases, oral lichen planus may even increase the risk of developing a type of skin cancer. It can also affect the scalp and nails. While the cause of most cases is unknown, some may be triggered by certain medications or hepatitis C infection. Treatment typically involves strong creams for localized cases and oral steroids for more widespread ones.
Lichen planus is a skin condition marked by purplish, flat-topped bumps and patches that can cause intense itching. These skin lesions can be distressing, especially when they affect the mouth or genitals severely. In severe cases, oral lichen planus may even increase the risk of developing a type of skin cancer. It can also affect the scalp and nails. While the cause of most cases is unknown, some may be triggered by certain medications or hepatitis C infection. Treatment typically involves strong creams for localized cases and oral steroids for more widespread ones.
Lichen planus er en tilstand, hvor immunsystemet forårsager betændelse, hvilket resulterer i markante mærker på huden og slimhinderne. Det rammer omkring 5% af voksne, oftere kvinder, og starter normalt omkring middelalderen. Oral involvering ses i op til 77% af tilfældene, hvilket mest påvirker den indre kind. Mens nogle mennesker måske ikke føler nogen symptomer, kan andre opleve smerte og have problemer med visse fødevarer (f. Eks. Sure, krydrede) eller tandpasta.
Lichen planus is an immune-mediated inflammatory condition leading to characteristic lesions on skin and mucous membranes. It presents in up to 5% of the general adult population with a female predilection (2:1); the onset is most commonly in middle age. Up to 77% of patients with lichen planus have oral disease, with buccal mucosa the most common subsite. The oral lesions may be asymptomatic, although a subset of patients have pain and difficulty tolerating certain foods (e.g., acidic, spicy) and toothpaste.
Lichen planus is an immune-mediated inflammatory condition leading to characteristic lesions on skin and mucous membranes. It presents in up to 5% of the general adult population with a female predilection (2:1); the onset is most commonly in middle age. Up to 77% of patients with lichen planus have oral disease, with buccal mucosa the most common subsite. The oral lesions may be asymptomatic, although a subset of patients have pain and difficulty tolerating certain foods (e.g., acidic, spicy) and toothpaste.
For at bekræfte diagnosen kutan lichen planus kan der laves en hudbiopsi. Direkte immunfluorescens (DIF) kan være nyttig hos patienter med bulløse læsioner til at differentiere tilstanden fra en autoimmun vesikulobulløs sygdom.