Mere information ― Dansk

Pigmented purpuric dermatoses (PPD) er en gruppe af hudsygdomme, der er præget af små områder med blødning under huden på grund af kapillærbetændelse. PPD starter typisk som røde til lilla pletter, der senere bliver gyldenbrune, når hæmosiderinet reabsorberes.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.

Schamberg disease er den mest almindelige type pigmented purpuric dermatoses (PPDs) , som er kroniske hudsygdomme karakteriseret ved små røde eller lilla pletter og øget hudfarve (pletter af brun, rød eller gul) . PPD'er er klassificeret i fem typer: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, and eczematoid-like purpura of Doucas and Kapetanakis. Schamberg disease (SD) er også kendt som progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressiva, and Schamberg's purpura. Det rammer hovedsageligt mænd og optræder typisk på underbenene, men kan også forekomme på lår, balder, krop eller arme.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.

Oplysninger om 113 patienter med PPD blev analyseret, herunder 38, der gennemgik hudbiopsi til denne undersøgelse. Den mest almindelige kliniske type var Schambergs sygdom (60,5%) . Andre tilstande ved siden af ​​PPD var hypertension (15,8%) , diabetes (10,5%) og andre. Medicinhistorier afslørede statiner (13,2%) , betablokkere (10,5%) og andre. Mulige faktorer forbundet med PPD omfattede nylig øvre luftvejsinfektion (5,3 %) , langvarig stående, der førte til højt ortostatisk tryk (2,6 %) og anstrengende træning (2,6 %) . Behandlingen blev givet til 36 patienter (94,7%) - oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.