Angioedema is a swelling (or edema) of the lower layer of skin or the mucous membranes. The swelling may occur in the face, tongue, and larynx. Often it is associated with hives, which are swelling within the upper skin.

The recent exposure to an allergen (e.g. peanuts) may the cause of the urticaria, but most cause of the urticaria is unknown.

The skin of the face, normally around the mouth, and the mucosa of the mouth and/or throat, as well as the tongue, swell over the period of minutes to hours. The swelling can be itchy or painful. Urticaria may develop simultaneously.

In severe cases, stridor of the airway occurs, with gasping or wheezy inspiratory breath sounds and decreasing oxygen levels. Tracheal intubation is required in these situations to prevent respiratory arrest and risk of death.

Treatment ― OTC Drugs
If you have trouble breathing, you should go to the emergency room quickly.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]

If symptoms are severe, epinephrine may be given subcutaneously or intramuscularly along with oral steroids.
#Epinephrine SC or IM
#Oral steroid or IV steroid
  • Allergic angioedema. This child is unable to open his eyes due to the swelling.
  • Angioedema
  • Angioedema of half of the tongue. Because the edema can block the airway, if you cannot breath well, go to the hospital as soon as possible.
  • Angioedema of the face
References Angioedema 30860724 
Angioedema is non-pitting edema that involves subcutaneous and/or submucosal layers of tissue that affects the face, lips, neck, and extremities, oral cavity, larynx, and/or gut. It becomes life-threatening when it involves the larynx.
 Urticaria and Angioedema: an Update on Classification and Pathogenesis 28748365