Angiofibroma is a hard papule, nodule, or tumor lesions. Angiofibromas are sometimes misdiagnosed as acne. They are termed on their locations :
1) face
Fibrous papule
2) penis
Pearly penile papule
3) underneath a fingernail or toenail
Periungual angiofibroma
  • Angiofibroma has a similar appearance to acne. The lesions mainly occur around the nose.
    References Cutaneous Angiofibroma 29494077 
    Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.