Angiokeratoma is a benign cutaneous lesion of capillaries, resulting in small marks of red to blue color and characterized by hyperkeratosis. Multiple angiokeratomas on the trunk in young people, may be "Fabry disease", genetic disorder connected with systemic complications.

Due to the rarity, angiokeratomas may be misdiagnosed as melanoma. A biopsy of the lesion can produce a more accurate diagnosis.

Diagnosis and Treatment
#Skin biopsy
  • Atypical case ― multiple Angiokeratoma; Most Angiokeratoma are single lesions.
  • It has a similar shape to melanoma, but is different from melanoma as it has soft and pliable features. The size of Angiokeratoma is usually smaller than what is shown in this picture. Angiokeratoma usually presents as a single lesion.
References Cutaneous Angiokeratoma Treated With Surgical Excision and a 595-nm Pulsed Dye Laser 36545640 
Angiokeratomas are vascular neoplasms with hyperkeratotic red to black papules and plaques, which may present as solitary or multiple lesions with variations in color, shape, and location. Successful treatment not only involves improvement of these symptoms but also cosmetic improvement. This report reviews 2 cases of cutaneous angiokeratoma treated with surgical excision and a 595-nm pulsed dye laser (PDL) in which the patients showed improvement of symptoms and cosmetic appearance. There are various types of angiokeratomas, and their extent, size, condition, and symptoms are different. Therefore, lesion-specific combined treatments may yield better results.
 Angiokeratoma circumscriptum - Case reports 33342183
Angiokeratoma circumscriptum is the rarest form of angiokeratoma, a condition mainly found in females. It shows up as dark-red to blue-black clusters of bumps or nodules on the lower limbs, typically in a pattern that's both segmental and on one side of the body.