Dermatofibroma is hard solitary slow-growing papules (rounded bumps) that usually brownish to tan; Although typical dermatofibromas cause little or no discomfort, itching and tenderness can occur. Dermatofibromas can be found anywhere on the body, but most often they are found on the legs and arms.

Dermatofibromas may be formed as a reaction to previous injuries such as insect bites or thorn pricks. Dermatofibromas are classed as benign skin lesions, meaning they are completely harmless, though Dermatofibromas may be confused with a variety of subcutaneous tumours. Deep penetrating dermatofibromas may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumours like "dermatofibrosarcoma protuberans".

Diagnosis and Treatment
Most are benign, but large lesions (>5 mm) may require biopsy.
#Skin biopsy
  • Typical case of Dermatofibroma ― A hard nodule on the limb. Dermatofibroma is a relatively common benign tumor.
References Dermatofibroma 29262213 
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
 Common Benign Skin Tumors 12613727
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, and epidermoid cysts is surgical removal. Cherry angiomas and sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons and seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.