Eczema herpeticum
Eczema herpeticum is a rare but severe disseminated infection that generally occurs at sites of skin damage produced by, for example, atopic dermatitis, burns, long-term usage of topical steroids or eczema.

This infectious condition appears as numerous vesicles superimposed on atopic dermatitis. it is often accompanied by fever and lymphadenopathy. Eczema herpeticum can be life-threatening in babies.

This condition is most commonly caused by herpes simplex virus. It can be treated with systemic antiviral drugs, such as acyclovir.

Diagnosis and Treatment
Misdiagnosis as eczema lesions (atopic dermatitis, etc.) and application of steroid ointment may exacerbate lesions.
  • Initially, it is often mistaken for atopic dermatitis, but it is actually an infectious disease caused by the herpes virus. It is characterized by the grouped lesion of small blisters and crusts of similar shape.
  • It is often mistaken for atopic dermatitis
  • Because it is a herpes virus infection, blisters and crusts are characteristically accompanied.
  • In most cases of Eczema herpeticum, atopic dermatatitis is usually present. If a large number of small blisters suddenly occur without a history of injuries, the diagnosis of herpes simplex virus infection should be considered.
  • Unlike atopic dermatitis, which includes various types of lesions, herpes simplex virus infection is composed of relatively uniform lesions.
References Eczema Herpeticum 32809616 
Eczema herpeticum (EH) is a disseminated cutaneous infection with herpes simplex virus that develops in a patient with atopic dermatitis. EH typically presents as a sudden onset eruption of monomorphic vesicles and punched-out erosions with hemorrhagic crusts over eczematous areas. Patients may have systemic symptoms, such as fever, lymphadenopathy, or malaise. Presentation ranges from mild and self-limiting in healthy adults to life-threatening in children, infants, and immunocompromised patients. Early treatment with antiviral therapy can shorten the duration of mild disease and prevent morbidity and mortality in severe cases.
 Eczema Herpeticum - Case reports 28813215
An 8-year-old girl with atopic dermatitis came in with a widespread outbreak of itchy, raised, red blisters with a small indentation in the center. Tests showed she had herpes simplex virus type 1.