Keratoacanthomahttps://en.wikipedia.org/wiki/Keratoacanthoma
Keratoacanthoma is a common, rapidly growing skin tumour, but it is unlikely to metastasize or invade. The lesion can resemble squamous cell carcinoma in appearance. Keratoacanthoma is most often found on sun‑exposed skin, especially the face, forearms, and hands.

Under the microscope, keratoacanthoma closely resembles squamous cell carcinoma. While some pathologists consider keratoacanthoma a distinct, non‑malignant entity, about 6 % of clinically and histologically diagnosed keratoacanthomas progress to invasive, aggressive squamous cell carcinoma.

○ Diagnosis and Treatment
#Dermoscopy
#Skin biopsy
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  • Typical Keratoacanthoma
  • This case appears similar to a wart.
References An Updated Review of the Therapeutic Management of Keratoacanthomas 36588786 
NIH
Keratoacanthoma (KA) is a common cutaneous tumor characterized by rapid growth and possible spontaneous regression. It most commonly affects older, fair-skinned males with significantly sun damaged skin. Although surgical removal with excision or Mohs micrographic surgery remains the standard of therapy, there are many alternative therapeutic modalities that can be utilized.
 A Clinical, Histopathological and Immunohistochemical Approach to the Bewildering Diagnosis of Keratoacanthoma 25191656 
NIH
Keratoacanthoma (KA) is a comparatively common low-grade tumor that initiates in the pilo-sebaceous glands and pathologically mimics squamous cell carcinoma (SCC). Essentially, strong debates confirm classifying keratoacanthoma as a variant of invasive SCC. The clinical behavior of KA is hardly predictable and the differential diagnosis of keratoacanthoma and other conditions with keratoacanthoma-like pseudocarcinomatous epithelial hyperplasia is challenging, both clinically and histopathologically.
 Intralesional Treatments for Invasive Cutaneous Squamous Cell Carcinoma 38201585 
NIH
Cutaneous squamous cell carcinoma (cSCC) is the second most frequent cancer in humans, and it is especially common in fragile, elderly people. Surgery is the standard treatment for cSCC but intralesional treatments can be an alternative in those patients who are either not candidates or refuse to undergo surgery. Classic intralesional treatments, including methotrexate or 5-fluorouracil, have been implemented, but there is now a landscape of active research to incorporate intralesional immunotherapy and oncolytic virotherapy into the scene, which might change the way we deal with cSCC in the future. In this review, we focus on intralesional treatments for cSCC (including keratoacanthoma), from classic to very novel strategies.