Xanthelasma is a sharply demarcated yellowish deposit of cholesterol underneath the skin. It usually occurs on or around the eyelids. While they are neither harmful to the skin nor painful, these minor growths may be disfiguring and can be removed. There is a growing body of evidence for the association between xanthelasma and blood low-density lipoprotein levels and increased risk of atherosclerosis.

Small lesions can be treated with lasers, but recurrence is very common.

  • It is characterized by bilateral symmetry. Recurrence is common even after laser treatment.
  • Xanthelasma palpebrarum
References Xanthelasma Palpebrarum 30285396 
Xanthelasma palpebrarum is primarily characterized by soft, lipid-rich deposits, especially cholesterol, manifesting as semisolid, yellowish papules or plaques. These deposits are typically found on the inner aspect of the eyes and are most commonly located along the corners of the upper and lower eyelids. Xanthelasma palpebrarum is a benign lesion and does not pose significant health risks. Approximately 50% of adult patients with xanthelasma have abnormal lipid levels. In younger individuals, particularly children, the presence of xanthelasma should prompt consideration of an underlying inherited dyslipidemia. Although xanthelasma treatment is typically not medically necessary, some patients may seek therapy for cosmetic reasons.