Xanthoma is a deposition of yellowish cholesterol-rich material that can appear anywhere in the body in various disease states. They are cutaneous manifestations of lipidosis in which lipids accumulate in large foam cells within the skin. They are associated with hyperlipidemias.

  • The patient's knee is showing multiple lesions.
    References Xanthoma 32965912 
    Xanthomas are localized lipid deposits within an organ system. Although innately benign, they are often an important visible sign of systemic diseases. Not all patients with hyperlipidemia or hypercholesterolemia develop xanthomas. However, the presence of xanthomatous lesions can serve as a unique and important clinical indicator of these metabolic states.