Amyloidosis - Amiloidosis
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En los resultados de 2022 del Stiftung Warentest de Alemania, la satisfacción del consumidor con ModelDerm fue sólo ligeramente inferior que con las consultas de telemedicina pagadas.
En los resultados de 2022 del Stiftung Warentest de Alemania, la satisfacción del consumidor con ModelDerm fue sólo ligeramente inferior que con las consultas de telemedicina pagadas.
Los rasgos faciales clásicos de la amiloidosis (Amyloidosis)
relevance score : -100.0%
ReferencesUna mujer de 26 años acudió a nuestra clínica quejándose de un sarpullido pruriginoso en las piernas que llevaba 10 años. A pesar de usar cremas con esteroides y crema de tazaroteno, la erupción no mejoró. No tenía antecedentes familiares relevantes. Al examinarla, encontramos parches elevados y ásperos en la zona anterior de sus piernas, que coincidían con una enfermedad llamada lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
Lichen Amyloidosis es una afección cutánea poco común, asociada a una picazón persistente de causa desconocida. Por lo general, se presenta como grupos de parches elevados y descoloridos en las superficies externas de la piel. Lichen Amyloidosis suele aparecer en personas de 50 a 60 años y, lamentablemente, no existe cura para ella. Los tratamientos disponibles actualmente suelen tener una eficacia limitada.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen amyloidosis es una afección cutánea con picor duradero. Se caracteriza por grupos de protuberancias engrosadas que aparecen principalmente en la espalda, las espinillas, los muslos y los brazos. Al examinarse al microscopio, Lichen amyloidosis muestra una acumulación de amiloide en la capa superior de la piel, acompañada de engrosamiento de la capa externa. Aunque aún no se comprende completamente la causa exacta de Lichen amyloidosis, estudios previos la han relacionado con factores como el roce o la fricción de la piel, la muerte celular, infecciones virales, entre otros. Lichen amyloidosis parece estar relacionada con otras afecciones cutáneas, como atopic dermatitis, lichen planus y mycosis fungoides.
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
○ Diagnóstico y tratamiento
#Electrophoresis of blood or urine
#Skin biopsy