Angiofibroma
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References
Cutaneous angiofibromas puede aparecer en varias partes del cuerpo. En la cara, suelen denominarse pápulas fibrosas o adenoma sebáceo; en el pene se llaman pearly penile papules ; debajo de la uña, se denominan angiofibromas periungueales o tumores de Koenen; y en la boca se les conoce como fibromas orales. Los angiofibromas faciales son una característica destacada de tuberous sclerosis (TS) , un trastorno hereditario que afecta la piel, los riñones, el corazón, el cerebro y los pulmones. Por lo general, se desarrollan en la cara durante la niñez o la edad adulta temprana en personas con ST. Tener tres o más angiofibromas faciales o dos o más angiofibromas periungueales se considera importante en el diagnóstico del ST. Además, pueden estar presentes múltiples angiofibromas faciales en las afecciones (multiple endocrine neoplasia type 1 (MEN-1) y Birt-Hogg-Dubé syndrome) . Pearly penile papules se encuentran a lo largo del margen coronal y el surco del pene. Son bultos persistentes e indoloros que se observan con mayor frecuencia en hombres no circuncidados.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
1) cara
Fibrous papule
2) pene
Pearly penile papule
3) debajo de la uña de la mano o del pie
Periungual angiofibroma