Amyloidosis - Amüloidoos
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Saksamaa 2022. aasta Stiftung Warentesti tulemustes oli tarbijate rahulolu ModelDermiga vaid veidi madalam kui tasuliste telemeditsiini konsultatsioonidega.
Saksamaa 2022. aasta Stiftung Warentesti tulemustes oli tarbijate rahulolu ModelDermiga vaid veidi madalam kui tasuliste telemeditsiini konsultatsioonidega.
Amüloidoosi (Amyloidosis) klassikalised näojooned
relevance score : -100.0%
ReferencesMeie kliinikusse tuli 26‑aastane naine, kellel oli sügelev lööve jalgadel, mis oli kestnud 10 aastat. Hoolimata steroidkreemide ja tazaroteeni kreemi kasutamisest ei paranenud lööve. Tal ei olnud asjakohast perekonnalugu. Uurides teda, leidsime tema säärte esiküljel kõrgendatud, karedaid laike, mis vastasid haigusele nimega lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
Lichen Amyloidosis on haruldane nahahaigus, mis on seotud teadmata põhjusega püsiva sügelusega. Tavaliselt ilmneb see naha välispindadel kõrgendatud, värvitud laikudena. Lichen Amyloidosis esineb peamiselt 50–60‑aastastel inimestel ning kahjuks ei ole selle vastu efektiivset ravi. Praegu saadaval olevad ravimeetodid ei ole tavaliselt tõhusad.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen amyloidosis on pikaajaline sügelev nahahaigus. See on tuntud peamiselt selja, säärte, reite ja käsivartide paksenenud punnide poolest. Mikroskoopia alt uurides näitab Lichen amyloidosis amüloidi kogunemist naha ülemisse kihisse koos välise nahakihi paksenemise ja suurenemisega. Kuigi Lichen amyloidosis täpne põhjus pole veel täielikult teada, on varasemad uuringud seostanud selle muu hulgas selliste teguritega nagu naha hõõrumine, rakusurm ja viirusnakkused. Tundub, et Lichen amyloidosis on seotud mitme teise nahahaigusega, näiteks atopic dermatitis, lichen planus ja mycosis fungoides.
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
○ Diagnostika ja ravi
#Electrophoresis of blood or urine
#Skin biopsy