Melasma
☆ Saksamaa 2022. aasta Stiftung Warentesti tulemustes oli tarbijate rahulolu ModelDermiga vaid veidi madalam kui tasuliste telemeditsiini konsultatsioonidega.
See on tavaline seisund, mida täheldatakse 40. eluaastate alguses Aasia naistel. Fotol olev ringikujuline kahjustus on pigem lentiigole kui melasmale lähemal.
References
Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
Hiljuti on low-fluence Q-switched Nd:YAG (LFQSNY) laser muutunud populaarseks melasma raviks, eriti Aasias. Erinevate uuringute kokkuvõte oli keeruline, kuid LFQSNY tundub traditsiooniliste ravimeetoditega võrreldes melasma jaoks üldiselt tõhus ja ohutu. Siiski on LFQSNY kõrvaltoimena teatatud mõnest laigulisest hüpopigmentatsioonist, mis võib olla tingitud suurest laserenergiast. LFQSNY agressiivne kasutamine võib põhjustada ka põletikust tingitud hüperpigmentatsiooni, eriti tumedamate nahatoonide korral.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Pigmentatsiooniprobleeme leitakse sageli esmatasandi arstiabis. Hüperpigmentatsioonihäirete levinumad tüübid on post-inflammatory hyperpigmentation, melasma, sunspots, freckles, and café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Melasmat ei saa teatud aja jooksul laserraviga lahendada, kuna tegemist on haigusega, mille puhul tekib pidevalt pigmenti. Trankseemhape aitab parandada pigmentatsiooni vähendamist.
○ Ravi
Mõnes riigis (nt Jaapan, Korea) on suukaudne traneksaamhape saadaval käsimüügis ja see on tõhus. Melasma kreem traneksaamhappe ja aselaiinhappega võib olla osaliselt abiks.
Hüdrokinooni võib paikselt kasutada hüperpigmentatsiooni raviks, kuid FDA peatas hüdrokinooni sisaldavad börsivälised tooted alates 2020. aastast.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma