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Pigmented purpuric dermatoses (PPD) on rühm nahahaigusi, mida iseloomustavad kapillaaride põletikust tingitud väikesed nahaalused verejooksud. PPD algab tavaliselt punaste kuni lillade laikudena, mis hiljem muutuvad hemosideriini uuesti imendumisel kuldpruuniks.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.

Schamberg disease on kõige levinum tüüp pigmented purpuric dermatoses (PPDs) , mis on kroonilised nahahaigused, mida iseloomustavad väikesed punased või lillad laigud ja naha värvuse suurenemine (pruunid, punased või kollased laigud) . PPD-d liigitatakse viide tüüpi: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, and eczematoid-like purpura of Doucas and Kapetanakis. Schamberg disease (SD) on tuntud ka kui progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressiva, and Schamberg's purpura. See mõjutab peamiselt mehi ja ilmneb tavaliselt sääreosadel, kuid võib esineda ka reitel, tuharatel, kehatüvel või kätel.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.

Analüüsiti teavet 113 PPD-ga patsiendi kohta, sealhulgas 38-le, kellele tehti selle uuringu jaoks naha biopsia. Kõige tavalisem kliiniline tüüp oli Schambergi tõbi (60,5%) . Teised haigusseisundid koos PPD-ga olid hüpertensioon (15,8%) , diabeet (10,5%) ja teised. Raviajalugu näitas statiine (13,2%) , beetablokaatoreid (10,5%) ja teisi. Võimalikud PPD-ga seotud tegurid olid hiljutine ülemiste hingamisteede infektsioon (5,3%) , pikaajaline seismine, mis põhjustas kõrge ortostaatilise rõhu (2,6%) , ja raske treening (2,6%) . Ravi manustati 36 patsiendile (94,7%) - oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.