Syphilis - Süüfilis
☆ Saksamaa 2022. aasta Stiftung Warentesti tulemustes oli tarbijate rahulolu ModelDermiga vaid veidi madalam kui tasuliste telemeditsiini konsultatsioonidega.
Chancres ― esmane süüfiliitnakkus Treponema pallidum poolt
References
Süüfilis on sugulisel teel leviv haigus, mida põhjustab bakter Treponema pallidum. Selles uuringus keskendume 57 sekundaarse süüfilisega patsiendile vanuses 18–68 aastat.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Süüfilis on Treponema pallidum'i põhjustatud bakteriaalne infektsioon. See võib jäljendada erinevaid haigusi, pälvides selle hüüdnime great imitator. Süüfilis mõjutab endiselt miljoneid kogu maailmas, kuid seda saab tõhusalt ravida penitsilliiniga.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum põhjustab süüfilist seksuaalse kontakti kaudu või emalt lapsele raseduse ajal. Kuigi selle diagnoosimiseks on olemas lihtsad testid ja ravi ühe pikatoimelise penitsilliinisüstiga toimib hästi, on süüfilis taas muutumas suureks probleemiks kogu maailmas. See kehtib eriti kõrge ja keskmise sissetulekuga riikides meeste seas, kes seksivad meestega (MSM) . Kuigi mõned madala sissetulekuga riigid on täitnud WHO eesmärgid peatada süüfilise ülekandumine emalt lapsele, on süüfilise arv HIV-positiivsete MSMide seas murettekitav.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Suurenenud maks: seda leitakse sageli ja see võib juhtuda koos põrna suurenemisega. Maksa biopsia uurimine tumevälja mikroskoopia all võib paljastada spiroheedi olemasolu. Maksafunktsiooni testid võivad näidata kõrvalekaldeid. (2) Naha kollasus (kollatõbi) : see, kas kellelgi on kollatõbi, sõltub sellest, kui palju maksa mõjutab. (3) Nohu: sageli üks esimesi märke, tavaliselt esimese nädala jooksul pärast sündi. (4) Lümfisõlmede turse: levinud on ka lümfisõlmede üldine turse, mis on tavaliselt valutu. (5) Nahalööve: lööve ilmneb tavaliselt üks kuni kaks nädalat pärast nohu. Võite näha väikeseid punaseid või roosasid laike seljal, tuharatel, reitel ja jalataldadel. See lööve võib areneda koorumise ja kooriku tekkeks.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Diagnostika ja ravi
VDRL-i ja RPR-i saab kasutada hiljutise nakatumise kinnitamiseks ja süüfilise skriinimiseks. FTA-ABS test on spetsiifilisem test ja seda saab kasutada varasema infektsiooni ajaloo kontrollimiseks. Penitsilliini kasutatakse süüfilise raviks.