Acanthosis nigricans
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References
Acanthosis nigricans azpiko egoera baten azaleko adierazpena da. Askotan larruazaleko tolesturetan agertzen da lepoan, besapeetan eta ingelean bezala, ertz argirik gabeko orban belusetsu ilunaren itxurarekin. Egoera hau diabetesarekin eta intsulinarekiko erresistentziarekin lotuta egon ohi da, baina kasu bakanetan, gorputzaren barruko minbizia adieraz dezake. Hormona arazoengatik edo esteroideak eta jaiotza-kontrolerako pilulak bezalako botika zehatzak hartzeagatik ere ager daiteke.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans (AN) larruazaleko gaixotasun arrunta da hainbat osasun arazorekin lotuta, hala nola intsulinarekiko erresistentzia, diabetesa, obesitatea, zenbait minbizi, hormona arazo eta botiken erreakzioekin. AN tratatzea azpiko osasun-arazoei aurre egitean zentratzen da. Hasieran, medikuek intsulinarekiko erresistentzia sindromearen seinaleak aztertzen dituzte, besteak beste, obesitatea, kolesterol altua, hipertentsioa eta 2 motako diabetesa. Medikuek sarritan topical retinoids errezetatzen dute lehen tratamendu aukera gisa, eta horrek larruazala loditzen lagun dezake. Hala ere, baliteke larruazala iluntzeari guztiz ez ematea. Salicylic acid, podophyllin, urea, and calcipotriol bezalako beste tratamendu-aukerek ere maiz aplikatu behar dute.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
○ Kausak
Normalean 40 urtetik beherako pertsonengan gertatzen da, genetikoki heredatua izan daiteke eta obesitatearekin edo endokrinopatiekin lotuta dago, hala nola, hipotiroidismoarekin, akromegaliarekin, obulutegi polikistikoan, intsulinarekiko erresistentziarako diabetesarekin edo Cushing gaixotasunarekin.
○ Tratamendua ― OTC Drogak
#40% urea cream